SCHEMBL4483862

SCHEMBL4483862

Cc1cccc(O[Ti](Oc2cccc(C)c2)(Oc2cccc(C)c2)Oc2cccc(C)c2)c1.c1ccc2c(O[Ti](Oc3cccc4ccccc34)(Oc3cccc4ccccc34)Oc3cccc4ccccc34)cccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.44
SLC6A4 P31645 3/20 0.44
ALDH1A1 P00352 5/20 0.44
GAA P10253 2/20 0.44
ACHE P22303 2/20 0.42
KCNA3 P22001 1/20 0.41
LMNA P02545 2/20 0.37
HTR1B P28222 3/20 0.36
HSD17B10 Q99714 2/20 0.36
PGR P06401 1/20 0.36
PTGS1 P23219 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR1D P28221 1/20 0.36
CYP2A6 P11509 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
BCHE P06276 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4304843 0.81 ACHE (0.60) SLC6A2SLC6A4ALDH1A1GAAACHE
SCHEMBL4307229 0.81 HTR1B (0.48) SLC6A4ALDH1A1GAAKCNA3HTR1B
SCHEMBL2354199 0.80 ALDH1A1 (0.62) SLC6A2SLC6A4ALDH1A1GAAACHE
SCHEMBL27888085 0.75 KCNA3 (0.64) SLC6A4ALDH1A1KCNA3LMNAHTR1B
SCHEMBL27888075 0.70 ALDH1A1 (0.56) ALDH1A1GAAKCNA3LMNATDP1
SCHEMBL1433070 0.70 LMNA (0.53) ALDH1A1GAALMNAHSD17B10PGR
SCHEMBL29039546 0.69 ALDH1A1 (0.60) ALDH1A1GAAACHELMNACYP2A6
SCHEMBL29080842 0.68 ALDH1A1 (0.58) ALDH1A1GAAACHELMNACYP2A6
SCHEMBL25690631 0.67 MRGPRX4 (0.61) ALDH1A1GAALMNAHTR1BMAPK1
SCHEMBL257604 0.67 HTT (0.45) SLC6A2SLC6A4ALDH1A1GAAKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618913-B2 Coordination catalyst containing an organosilicon compound , nitrogen compound, transition metal compound and magnesiumon compound on catalyst support FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-11-17 US disclosed
WO-2008027479-A2 HIGHLY ACTIVE ALPHA-OLEFIN COPOLYMERIZATION CATALYST SYSTEM FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2008-03-06 WO disclosed
US-20080058198-A1 Highly active alpha-olefin copolymerization catalyst system FORMOSA PLASTICS CORPORATION, U.S.A. 2008-03-06 US disclosed
US-7307036-B2 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION U.S.A. (US) 2007-12-11 US disclosed
US-6992034-B2 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2006-01-31 US disclosed
US-20060019821-A1 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2006-01-26 US disclosed
US-20050009690-A1 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATIONS, U.S.A. 2005-01-13 US disclosed
US-6034188-A Process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 2000-03-07 US disclosed