Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493111 | 0.75 | — | — | |
| Potassium Ion SCHEMBL2276432 | 0.58 | — | — | |
| Potassium Ion SCHEMBL29628051 | 0.58 | — | — | |
| Potassium Ion SCHEMBL23462131 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462035 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462233 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462274 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462130 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462163 | 0.50 | CA4 (0.50) | — | |
| Potassium Ion SCHEMBL23462189 | 0.50 | CA4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528266-B2 | Chemical intermediates of byproduct-free 7-thio-3H-isobenzofuran-1-one derivatives and herbicidal 7-[(4,6-dimethoxy-pyrimidin-2-yl)thio]-3-methyl-3H-isobenzo-furan-1-one | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| US-20080108813-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080097111-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-7307175-B2 | Process for the preparation of 7-substituted 3-alkyl-3H-isobenzofuran-1-one derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-12-11 | — | — | US | disclosed |
| US-20040158080-A1 | Process for the preparation of 7-substituted 3-alkyl-3h-isobenzofuran-1-one derivatives | SYNGENTA CROP PROTECTION, INC. | 2004-08-12 | — | — | US | disclosed |
| EP-1390339-A2 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | Syngenta Participations AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002094760-A2 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED 3-ALKYL-3H-ISOBENZOFURAN-1-ONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-11-28 | — | — | WO | disclosed |