⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28149608 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28330748 | 0.98 | ALDH1A1 (0.33) | — | |
| Trimethylammonium SCHEMBL27814634 | 0.92 | LMNA (0.33) | — | |
| Biphenyl SCHEMBL28988945 | 0.89 | ALDH1A1 (0.41) | — | |
| SCHEMBL28492266 | 0.80 | ERN1 (0.31) | — | |
| Indole SCHEMBL28064365 | 0.80 | TRPA1 (0.50) | — | |
| SCHEMBL28183756 | 0.78 | — | — | |
| SCHEMBL28202562 | 0.77 | — | — | |
| SCHEMBL3206352 | 0.77 | — | — | |
| SCHEMBL29006143 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330881-A | Synthesis method of 3-aminomethyl-1-H pyrazole | 苏州汉德创宏生化科技有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-117779130-B | Wafer electroplated tungsten alloy solution, preparation method and electroplating method | 昆山一鼎工业科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-116120324-A | Preparation method of purified allopurinol | 宜兴市星宇药业有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-111978306-B | Furanol pyrazole formamide derivative and preparation method and application thereof | 湖南大学 | 2023-01-03 | — | — | CN | claimed |
| CN-114685371-A | Pyrazole carboxamide derivatives, their preparation and use | 四川大学 | 2022-07-01 | — | — | CN | claimed |
| CN-110520127-A | Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 | TAKEDA PHARMACEUTICALS CO | 2019-11-29 | — | — | CN | claimed |
| CN-104592251-B | 4- (condensed hetero ring substituted-amino) -1H- pyrazole-3-formamide class compound and application thereof | 上海复星医药产业发展有限公司 | 2019-10-01 | — | — | CN | claimed |
| CN-110177783-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-109970717-A | 4- (cycloaliphatic ring and pyrimidine/pyridine replaces) amino -1H-3- pyrazole carboxamides FLT3 inhibitor and application thereof | 中国药科大学 | 2019-07-05 | — | — | CN | claimed |
| CN-106715415-B | 3-amino-1, 5,6, 7-tetrahydro-4H-indol-4-ones | 拜耳制药股份公司 | 2019-06-14 | — | — | CN | claimed |
| CN-101312725-A | Hexahydro-cyclooctyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-11-26 | — | — | CN | claimed |
| US-20080275022-A1 | Substituted Quinazolones as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | US | claimed |
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | claimed |
| CN-101048153-A | Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of diabetes mellitus type I, obesity and related conditions | SOLVAY PHARM GMBH | 2007-10-03 | — | — | CN | claimed |
| CN-1993331-A | N- (1- (1-benzyl -4-phenyl-1h-imidazol-2-yl) -2,2-dymethylpropyl) benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer | CHIRON CORP (US) | 2007-07-04 | — | — | CN | claimed |
| EP-1761506-A1 | SUBSTITUTED QUINAZOLONES AS ANTI-CANCER AGENTS | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | claimed |
| CN-1925856-A | Pharmaceutical composition for oral administration of pyrazole-3-carboxamide derivatives | SANOFI AVENTIS (FR) | 2007-03-07 | — | — | CN | claimed |
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | claimed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | claimed |
| WO-2005123696-A1 | SUBSTITUTED QUINAZOLONES AS ANTI-CANCER AGENTS | ASTRAZENECA AB (SE) | 2005-12-29 | — | — | WO | claimed |