Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44842 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL28330748 | 0.87 | ALDH1A1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28149608 | 0.87 | — | — | |
| Trimethylammonium SCHEMBL27814634 | 0.81 | LMNA (0.33) | ALDH1A1 | |
| Indole SCHEMBL28064365 | 0.78 | TRPA1 (0.50) | ALDH1A1MAPTNPC1RAB9AFAAH | |
| SCHEMBL28492266 | 0.74 | ERN1 (0.31) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3420311 | 0.73 | NPC1 (0.59) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL212774 | 0.73 | ACHE (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2322234 | 0.70 | RAB9A (0.56) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL14418354 | 0.70 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880765-B | 4- (1H-pyrazol-1-yl) biphenyl formamide compound containing diphenyl ether group and application thereof | 南京林业大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-113880765-A | Diphenyl ether group-containing 4- (1H-pyrazole-1-yl) biphenyl formamide compound and application thereof | 南京林业大学 | 2022-01-04 | — | — | CN | disclosed |