Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808654 | 0.85 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL24143107 | 0.85 | LTA4H (0.47) | HDAC6 | |
| SCHEMBL30768239 | 0.85 | LMNA (0.47) | — | |
| SCHEMBL23500484 | 0.85 | LMNA (0.47) | — | |
| SCHEMBL24142430 | 0.83 | LTA4H (0.46) | — | |
| SCHEMBL25808664 | 0.83 | RAB9A (0.43) | — | |
| SCHEMBL24143191 | 0.82 | LMNA (0.35) | HDAC6 | |
| SCHEMBL25760237 | 0.80 | MMP1 (0.35) | — | |
| SCHEMBL24923066 | 0.80 | MMP1 (0.37) | HDAC6 | |
| SCHEMBL26735216 | 0.80 | GBA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498350-B2 | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2009-03-03 | — | — | US | disclosed |
| US-7498350-B2 | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2009-03-03 | — | — | US | disclosed |
| US-20060116386-A1 | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
| CN-1742009-A | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116386-A1 | Oxazolidinones as antibacterial agents | MRPL21, MRPS23, DPP3 | MAOB 120/4885HDAC6 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.