SCHEMBL448757

SCHEMBL448757

C1=CCc2ccccc2NC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 2/20 0.34
AHR P35869 1/20 0.34
PDK2 Q15119 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HSP90AA1 P07900 1/20 0.34
THRB P10828 1/20 0.34
HK1 P19367 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
HKDC1 Q2TB90 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21126434 0.87 ALOX15 (0.41) ALOX15HSD17B10GAANPSR1NPC1
SCHEMBL293794 0.79 ALOX15 (0.45) ALOX15HSD17B10GAANPSR1NPC1
SCHEMBL24727248 0.78 ALOX15 (0.41) ALOX15HSD17B10GAANPSR1NPC1
SCHEMBL20627590 0.78 ALOX15 (0.41) ALOX15HSD17B10GAANPSR1NPC1
SCHEMBL9529806 0.71 DRD2 (0.53) HSD17B10HSP90AA1
SCHEMBL44447 0.71 TSHR (0.44) HTR2CCA9
SCHEMBL29507678 0.71 TSHR (0.44) HTR2CCA9
SCHEMBL170456 0.70 PLAU (0.43) ALOX15HSD17B10GAANPSR1NPC1
SCHEMBL29504825 0.70 PLAU (0.43) ALOX15HSD17B10GAANPSR1NPC1
Methane SCHEMBL27705728 0.68 TSHR (0.42) HTR2CCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071494-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-122071492-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
CN-112236434-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2024-02-23 CN claimed
US-20240052256-A1 BENZAZEPINE COMPOUNDS AS ANTIOXIDANTS FOR LUBRICANT COMPOSITIONS THE LUBRIZOL CORPORATION 2024-02-15 US claimed
EP-4267707-A1 BENZAZEPINE COMPOUNDS AS ANTIOXIDANTS FOR LUBRICANT COMPOSITIONS The Lubrizol Corporation (US) 2023-11-01 EP claimed
CN-116685663-A Benzazepine compounds as antioxidants for lubricating compositions 路博润公司 2023-09-01 CN claimed
WO-2022140496-A1 BENZAZEPINE COMPOUNDS AS ANTIOXIDANTS FOR LUBRICANT COMPOSITIONS THE LUBRIZOL CORPORATION (US) 2022-06-30 WO claimed
CN-113861128-A Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2021-12-31 CN claimed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP claimed
US-8153625-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-10 US claimed
US-7759336-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-07-20 US claimed
US-6903118-B1 Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides KLINGE PHARMA GMBH (DE) 2005-06-07 US claimed
EP-0347672-B1 Benzazepine derivatives NOVO NORDISK AS (DK) 1994-03-02 EP claimed
EP-0080012-B1 6-CHLORO-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE, ITS ACID ADDITION SALTS AND ITS USE AS AN INTERMEDIATE SMITHKLINE BECKMAN CORPORATION (US) 1986-04-09 EP claimed
CN-122071493-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071495-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
CN-122071496-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN disclosed
EP-0007070-B1 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS HAVING DOPAMINE RECEPTOR BLOCKING ACTIVITY SMITHKLINE BECKMAN CORPORATION (US) 1983-01-19 EP disclosed
US-4265890-A ANTIPSYCHOTIC, ANTIEMETICS SMITHKLINE CORPORATION (US) 1981-05-05 US disclosed
EP-0007070-A1 2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity SMITHKLINE BECKMAN CORPORATION (US) 1980-01-23 EP disclosed