SCHEMBL560892

SCHEMBL560892

NNc1cccc(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.50
KMT2A Q03164 7/20 0.50
LMNA P02545 7/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
PNMT P11086 2/20 0.44
MAPT P10636 4/20 0.44
MAPK1 P28482 1/20 0.43
TSHR P16473 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL20984135 0.98 MEN1 (0.48) MEN1KMT2ALMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL29502259 0.98 MEN1 (0.48) MEN1KMT2ALMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL670341 0.98 MEN1 (0.48) MEN1KMT2ALMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL4698984 0.95 MEN1 (0.47) MEN1KMT2ALMNAKDM4EALDH1A1
Oxalic Acid SCHEMBL20984279 0.88 MEN1 (0.55) MEN1KMT2ALMNAKDM4EALDH1A1
Phosphoric Acid SCHEMBL20984142 0.88 MEN1 (0.50) MEN1KMT2ALMNAKDM4EALDH1A1
Sulfuric Acid SCHEMBL20984124 0.88 MEN1 (0.50) MEN1KMT2ALMNAKDM4EALDH1A1
Nitric Acid SCHEMBL20984111 0.84 MEN1 (0.47) MEN1KMT2ALMNAKDM4EALDH1A1
SCHEMBL29573773 0.79
SCHEMBL6893 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727199-A A kind of method that hexahydrotoluene substitutes toluene production DCB 3,3' dichlorobenzidine hydrochloride 山东隆信药业有限公司 2018-11-02 CN claimed
CN-108715578-A A kind of method that dimethyl carbonate substitutes toluene production DCB 3,3' dichlorobenzidine hydrochloride 山东隆信药业有限公司 2018-10-30 CN claimed
EP-0918052-B1 Improved polymeric mdi color BAYER AG (US) 2003-05-28 EP claimed
US-5942151-A PREVENTING THE DISCOLORATION OF PRODUCING POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE BY ADDING AN ADDITIVE HYDRAZINE OR A HYDRAZINE DERIVATIVE BAYER CORPORATION (US) 1999-08-24 US claimed
EP-0918052-A1 Improved polymeric mdi color Bayer Corporation (US) 1999-05-26 EP claimed
US-4094906-A INSECTICIDES AND MITICIDES THE UPJOHN COMPANY (US) 1978-06-13 US claimed
US-RE50878-E1 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-05 US disclosed
US-20240150356-A1 Pyrimidine amide compounds and use thereof ALPHALA CO., LTD. (TW) 2024-05-09 US disclosed
US-20240018138-A1 PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS VENTUS THERAPEUTICS U.S., INC. 2024-01-18 US disclosed
US-20240018138-A1 PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS VENTUS THERAPEUTICS U.S., INC. 2024-01-18 US disclosed
WO-2023183275-A1 HEXAHYDROPYRIDO[4,3-B]INDOLYL KETONE DERIVATIVES USEFUL AS CGAS MODULATORS VENTUS THERAPEUTICS U.S., INC. (US) 2023-09-28 WO disclosed
CN-112409203-B Method for simultaneously synthesizing phenylhydrazine salt and pyruvic acid or glyoxylic acid 帕潘纳(北京)科技有限公司 2022-10-25 CN disclosed
US-20210147408-A1 SMALL MOLECULE INHIBITORS OF GALECTIN-3 BRISTOL MYERS SQUIBB CO (US) 2021-05-20 US disclosed
EP-0083613-A1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES. MAY & BAKER LTD (GB) 1983-07-20 EP disclosed
WO-1983000332-A1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES MAY & BAKER LTD (GB) 1983-02-03 WO disclosed
US-4351948-A Imidazole hydrazone derivatives G.D. SEARLE & CO. (US) 1982-09-28 US disclosed
EP-0007972-B1 PROCESS FOR THE PREPARATION OF DICHLORO-HYDRAZOBENZENES BY CATALYTIC HYDROGENATION OF MONOCHLORO-NITROBENZENES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1982-07-21 EP disclosed
EP-0007972-A1 Process for the preparation of dichloro-hydrazobenzenes by catalytic hydrogenation of monochloro-nitrobenzenes HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1980-02-20 EP disclosed
US-4009181-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-02-22 US disclosed
US-3987234-A ACRYLIC ESTER POLYMERS HENKEL & CIE G.M.B.H. (DT) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147408-A1 SMALL MOLECULE INHIBITORS OF GALECTIN-3 LGALS3, LGALS1, LGALS3BP MEN1 2006/4885KMT2A 4698/4885LMNA 1476/4885
US-20240018138-A1 PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS CGAS, LRRK2, ADSS2 MEN1 972/4885KMT2A 4588/4885LMNA 327/4885
US-20240150356-A1 Pyrimidine amide compounds and use thereof TYMP, DPYD, TYMS MEN1 1817/4885KMT2A 3140/4885LMNA 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.