SCHEMBL448980

SCHEMBL448980

C=C(CCCCCCCCCCCCCCCCCCCCCCCCCCCCC)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.58
PPARG P37231 7/20 0.58
PPARD Q03181 7/20 0.58
PPARA Q07869 7/20 0.58
HDAC11 Q96DB2 5/20 0.58
TSHR P16473 4/20 0.58
PTPN1 P18031 3/20 0.58
ALDH1A1 P00352 2/20 0.58
TLR2 O60603 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
FABP4 P15090 2/20 0.58
KMT2A Q03164 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
SLC22A8 Q8TCC7 1/20 0.58
MEN1 O00255 1/20 0.58
ESR1 P03372 1/20 0.58
ALOX15 P16050 1/20 0.58
PDE4A P27815 1/20 0.58
PDE3A Q14432 1/20 0.58
HSD17B10 Q99714 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145961 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL27157 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL153388 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10794679 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL1119569 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL148286 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL3947983 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL147810 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL3435975 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL149654 1.00 GPR84 (0.58) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1837391-B1 GREASE COMPOSITION AND GREASE-SEALED ROLLER BEARING NTN TOYO BEARING CO LTD (JP) 2011-02-09 EP claimed
US-20090130038-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST ONE ESTER OF A C8-C24 FATTY ACID AND OXYETHYLENATED SORBITAN COMPRISING 2 TO 10 OXYETHYLENE MOTIFS, AND COSMETIC TREATMENT METHODS EMPLOYING SAID COMPOSITIONS L'OREAL S.A. (FR) 2009-05-21 US claimed
EP-3935143-B1 IMPROVED HYDROCARBON LUBRICANT COMPOSITIONS AND METHOD TO MAKE THEM DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-29 EP disclosed
US-11584896-B2 Hydrocarbon lubricant compositions and method to make them DOW GLOBAL TECHNOLOGIES LLC (US) 2023-02-21 US disclosed
US-20220119728-A1 IMPROVED HYDROCARBON LUBRICANT COMPOSITIONS AND METHOD TO MAKE THEM DOW GLOBAL TECHNOLOGIES LLC 2022-04-21 US disclosed
CN-107001524-B Polymer and method of making same 住友化学株式会社 2020-11-17 CN disclosed
EP-2009083-B1 LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2017-03-08 EP disclosed
US-8900333-B2 Biodiesel cold flow improver BASF SE (DE) 2014-12-02 US disclosed
US-8846017-B2 Cosmetic compositions comprising at least one cationic copolymer and at least one amino silicone and methods of use thereof L'OREAL (FR) 2014-09-30 US disclosed
US-8846589-B2 Lubricating oil composition for transmission NIPPON OIL CORPORATION (JP) 2014-09-30 US disclosed
US-8728997-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2014-05-20 US disclosed
US-20090131291-A1 LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2009-05-21 US disclosed
US-20090074699-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE AMINO SILICONE AND METHODS OF USE THEREOF L'OREAL S.A. (FR) 2009-03-19 US disclosed
EP-2009083-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2008-12-31 EP disclosed
US-20070270320-A1 LUBRICANT COMPOSITION FOR AUTOMATIC TRANSMISSION NIPPON OIL CORPORATION (JP) 2007-11-22 US disclosed
EP-1847585-A2 Lubricant composition for automatic transmission Nippon Oil Corporation (JP) 2007-10-24 EP disclosed
US-20070191239-A1 LUBRICATING OIL COMPOSITION FOR TRANSMISSION NIPPON OIL CORPORATION (JP) 2007-08-16 US disclosed
EP-1808476-A1 LUBRICANT COMPOSITION FOR TRANSMISSION Nippon Oil Corporation (JP) 2007-07-18 EP disclosed
US-20070112142-A1 Release agent composition and release liner LINTEC CORPORATION (JP) 2007-05-17 US disclosed
EP-1723945-A1 Hair cleaning compositions with optimised rheological behaviour Henkel Kommanditgesellschaft auf Aktien (DE) 2006-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074699-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE AMINO SILICONE AND METHODS OF USE THEREOF KRT18, CUTA, C1R GPR84 1684/4885PPARG 3629/4885PPARD 3982/4885
US-20090130038-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST ONE ESTER OF A C8-C24 FATTY ACID AND OXYETHYLENATED SORBITAN COMPRISING 2 TO 10 OXYETHYLENE MOTIFS, AND COSMETIC TREATMENT METHODS EMPLOYING SAID COMPOSITIONS FABP4, FFAR4, ANXA4 GPR84 577/4885PPARG 322/4885PPARD 583/4885
US-20070191239-A1 LUBRICATING OIL COMPOSITION FOR TRANSMISSION MUC1, FUT8, F12 GPR84 193/4885PPARG 3763/4885PPARD 4506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.