Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048801 | 1.00 | HTR2A (0.39) | HTR2ACYP2A6CA1CA2CA5A | |
| SCHEMBL4509253 | 1.00 | HTR2A (0.39) | HTR2ACYP2A6CA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL4513936 | 0.98 | HTR2A (0.38) | HTR2ACYP2A6CA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL1864740 | 0.98 | HTR2A (0.38) | HTR2ACYP2A6CA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL16653694 | 0.98 | HTR2A (0.38) | HTR2ACYP2A6CA1CA2CA5A | |
| SCHEMBL20639987 | 0.84 | IGF1R (0.47) | ALDH1A1MAPK1 | |
| SCHEMBL4490669 | 0.82 | CES1 (0.43) | CA1CA2DPP4DPP7 | |
| SCHEMBL296872 | 0.78 | IDO1 (0.44) | CA1CA2CA9ESR1ESR2 | |
| SCHEMBL14305986 | 0.78 | IDO1 (0.44) | CA1CA2CA9ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL25187772 | 0.76 | IDO1 (0.46) | HTR2AESR1ESR2PDE2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12247233-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2025-03-11 | — | — | US | claimed |
| US-20220290197-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2022-09-15 | — | — | US | claimed |
| US-11371067-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2022-06-28 | — | — | US | claimed |
| US-20200362377-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-11-19 | — | — | US | claimed |
| EP-2446026-B1 | TRANSAMINASE REACTIONS | CODEXIS INC (US) | 2017-08-09 | — | — | EP | claimed |
| US-9434968-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2016-09-06 | — | — | US | claimed |
| CN-102597226-B | Transamination reaction | CODEXIS, INC. (US) | 2015-08-19 | — | — | CN | claimed |
| US-20150079640-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-03-19 | — | — | US | claimed |
| US-8921079-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2014-12-30 | — | — | US | claimed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | claimed |
| WO-2025059027-A1 | CYCLOPENTA[E]PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS MALT1 INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| US-12247233-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| EP-4228647-A1 | MALT1 MODULATORS AND USES THEREOF | Rheos Medicines, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20220290197-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2022-09-15 | — | — | US | disclosed |
| US-11371067-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-20070155739-A1 | Substituted bis-amide metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155739-A1 | Substituted bis-amide metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-7154005-B2 | Synthesis of alpha fluoroalkyl amines | MERCK FROSST CANADA, LTD. (CA) | 2006-12-26 | — | — | US | disclosed |
| WO-2006133559-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | MERCK FROSST CANADA LTD. (CA) | 2006-12-21 | — | — | WO | disclosed |
| US-20060052642-A1 | Synthesis of alpha fluoroalkyl amines | MERCK CANADA INC. (CA) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052642-A1 | Synthesis of alpha fluoroalkyl amines | ADH5, ADH1C, INMT | HTR2A 712/4885CYP2A6 1218/4885CA1 4148/4885 |
| US-20070155739-A1 | Substituted bis-amide metalloprotease inhibitors | MMP13, MMP9, ADAMTS13 | HTR2A 3202/4885CYP2A6 468/4885CA1 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.