SCHEMBL449110

SCHEMBL449110

Cc1ccc(-c2cccc(OP(=O)(O)O)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 6/20 0.47
INPP5A Q14642 3/20 0.47
INPP5B P32019 2/20 0.47
SRC P12931 5/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
PDE3A Q14432 1/20 0.39
HSD17B10 Q99714 1/20 0.39
AKT1 P31749 1/20 0.38
LMNA P02545 4/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936078 0.86 INPPL1 (0.43) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL848184 0.86 INPPL1 (0.49) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL3686702 0.86 INPPL1 (0.49) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL29604346 0.85 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL4451434 0.85 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL343312 0.85 INPPL1 (0.47) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL1160770 0.84 INPPL1 (0.47) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL1792078 0.84 INPPL1 (0.44) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL31730227 0.82 INPPL1 (0.45) INPPL1INPP5AINPP5BSRCALDH1A1
SCHEMBL23795077 0.81 SRC (0.44) INPPL1INPP5AINPP5BSRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857454-B1 POLYLACTIC ACID RESIN COMPOSITION KAO CORP (JP) 2018-07-04 EP claimed
US-9725593-B2 Polylactic acid resin composition KAO CORPORATION (JP) 2017-08-08 US claimed
EP-2857454-A1 POLYLACTIC ACID RESIN COMPOSITION Kao Corporation (JP) 2015-04-08 EP claimed
US-20150091211-A1 POLYLACTIC ACID RESIN COMPOSITION KAO CORPORATION (JP) 2015-04-02 US claimed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator IDEMITSU KOSAN CO., LTD. (JP) 2026-01-27 US disclosed
EP-4108744-B1 REFRIGERATOR OIL COMPOSITION AND MIXED COMPOSITION FOR REFRIGERATOR IDEMITSU KOSAN CO (JP) 2025-11-19 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed
US-4322516-A Copolymers for pressure-sensitive adhesives based on acrylic esters, (meth)acrylamide vinyl acetate and ethylene WACKER-CHEMIE GMBH (DE) 1982-03-30 US disclosed
US-4296017-A ETHYLENE, VINYL ACETATE, N-VINYL-2-PYRROLIDONE, VINYL LOWER ALKANOATE, OTHER UNSATURATED ESTER, LAMINATION WACKER-CHEMIE GMBH (DE) 1981-10-20 US disclosed
US-4246158-A DIELECTRICS, SHEATHS IN ELECTRICAL CONDUCTORS WACKER-CHEMIE GMBH (DE) 1981-01-20 US disclosed
US-4206067-A Thermally stabilized erosion-inhibited functional fluids containing perhalometal compounds and an organic base CHEVRON RESEARCH COMPANY (US) 1980-06-03 US disclosed
US-3931022-A MINERAL OIL, HETEROCYCLIC ANTIOXIDANT, C(8-10)CARBOXYLIC ACID, TRICRESYL PHOSPHATE, ALKYLPHENOL TEXACO INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK INPPL1 594/4885INPP5A 1449/4885INPP5B 1127/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 INPPL1 3106/4885INPP5A 4339/4885INPP5B 3097/4885
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator F9, CA2, F8 INPPL1 686/4885INPP5A 2394/4885INPP5B 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.