Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | GLA | P06280 | 6/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491647 | 1.00 | RAB9A (0.43) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL10809388 | 0.88 | NPC1 (0.46) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL10809391 | 0.88 | NPC1 (0.46) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL2079811 | 0.81 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL2079808 | 0.81 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL4467298 | 0.81 | KDM4E (0.58) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL4467304 | 0.81 | KDM4E (0.58) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL27579766 | 0.76 | KMT2A (0.47) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL27597553 | 0.75 | CYP24A1 (0.46) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 | |
| SCHEMBL13328382 | 0.75 | ELANE (0.51) | RAB9ASMN1; SMN2NPC1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557123-B2 | Heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1403253-A1 | NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | GPR119, INSR, GLP1R | RAB9A 2622/4885SMN1; SMN2 3304/4885NPC1 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.