Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471074 | 0.86 | PGR (0.51) | PGRAR | |
| SCHEMBL80296 | 0.72 | PGR (0.57) | PGRAR | |
| SCHEMBL79962 | 0.70 | PGR (0.60) | PGRAR | |
| SCHEMBL80297 | 0.70 | PGR (0.60) | PGRAR | |
| SCHEMBL13579113 | 0.69 | PGR (0.77) | PGRAR | |
| SCHEMBL79961 | 0.69 | PGR (0.57) | PGRAR | |
| SCHEMBL4809621 | 0.66 | PGR (1.00) | PGRAR | |
| SCHEMBL5498420 | 0.66 | PGR (0.65) | PGRAR | |
| SCHEMBL5436855 | 0.66 | PGR (1.00) | PGRAR | |
| SCHEMBL2884729 | 0.66 | PGR (0.62) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572824-B2 | Methods for minimizing thioamide impurities | WYETH (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1732922-B1 | METHODS FOR MINIMIZING THIOAMIDE IMPURITIES | WYETH CORP (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20080071083-A1 | Methods for minimizing thioamide impurities | WYETH (US) | 2008-03-20 | — | — | US | disclosed |
| US-7314932-B2 | Methods for minimizing thioamide impurities | WYETH (US) | 2008-01-01 | — | — | US | disclosed |
| US-20050228179-A1 | Methods for minimizing thioamide impurities | WYETH (US) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228179-A1 | Methods for minimizing thioamide impurities | TST, TXN, TTR | PGR 3997/4885AR 1924/4885 |
| US-20080071083-A1 | Methods for minimizing thioamide impurities | TST, TPMT, TXN | PGR 4456/4885AR 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.