Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183624 | 0.80 | METAP1 (0.43) | ALDH1A1NPC1RAB9AHPGDADORA1 | |
| SCHEMBL29459210 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL40372 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Lithium SCHEMBL6552341 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6552336 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL28338025 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL4479100 | 0.74 | CHEK1 (0.42) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL33527682 | 0.74 | TSHR (0.46) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL14864794 | 0.73 | ADORA1 (0.50) | ALDH1A1RAB9AHPGDADORA1PNMT | |
| SCHEMBL20024355 | 0.72 | ALDH1A1 (0.47) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635781-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1387827-B1 | SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1387827-B1 | SYNTHESIS OF CYCLOPENTADIENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-24 | — | — | EP | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-7253292-B2 | Synthesis of cyclopentadiene derivatives | BASELL POLYOLEFINE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | EQUISTAR CHEMICALS, LP | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236115-A1 | Synthesis of cyclopentadiene derivatives | CYCS, DHPS, CBR1 | ALDH1A1 1619/4885NPC1 1696/4885PLA2G1B 4688/4885 |
| US-20080287692-A1 | Synthesis of cyclopentadiene derivatives | CYCS, CYC1, CBR1 | ALDH1A1 1577/4885NPC1 1621/4885PLA2G1B 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.