SCHEMBL4494018

SCHEMBL4494018

CC(C)(C)OC(=O)OC=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
ELANE P08246 1/20 0.36
DGAT1 O75907 1/20 0.36
HDAC6 Q9UBN7 3/20 0.35
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
CTSK P43235 3/20 0.32
HDAC3 O15379 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187395 0.79 ELANE (0.36) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL27835583 0.77 TDP1 (0.38) TDP1DGAT1HDAC6HDAC1HDAC2
SCHEMBL5539990 0.77 HDAC6 (0.38) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL1128473 0.77
SCHEMBL17300712 0.77 ALDH1A1 (0.33) TDP1
SCHEMBL29121 0.76 DGAT1 (0.46) TDP1ELANEDGAT1HDAC6HDAC1
SCHEMBL12604849 0.75 ELANE (0.34) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL2639330 0.75 ELANE (0.34) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL4494016 0.75 TDP1 (0.36) TDP1ELANEDGAT1HDAC6HDAC1
Fluoride SCHEMBL2692246 0.74 DGAT1 (0.43) TDP1ELANEDGAT1HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119996392-A Method, system, equipment and storage medium for efficiently decoding GTS (gateway transport stream) water level message data 国家海洋环境预报中心 2025-05-13 CN claimed
CN-119311333-B Method for realizing MaaS platform operation ecologization based on large model evaluation technology 浩鲸云计算科技股份有限公司 2025-03-18 CN claimed
CN-119311333-A Method for realizing MaaS platform operation ecologization based on large model evaluation technology 浩鲸云计算科技股份有限公司 2025-01-14 CN claimed
CN-113379677-B Static stacking CO60 radioactive source early warning method based on artificial intelligence 南京新频点电子科技有限公司 2024-07-12 CN claimed
CN-112149722-B Image automatic labeling method based on unsupervised domain adaptation 南京大学 2024-01-16 CN claimed
CN-115968086-A Classroom energy-saving lamp control system based on image recognition and control method thereof 西安电子科技大学 2023-04-14 CN claimed
CN-114044772-A Epipiprazole synthesis method and intermediate thereof 浙江国邦药业有限公司 2022-02-15 CN claimed
US-20260147459-A1 SYSTEMS AND METHODS FOR DYNAMIC USER INTERFACE INTERACTIONS Signet Health Corporation (US) 2026-05-28 US disclosed
US-12579594-B1 Systems and methods for dynamically updating data for course generation BH Operations, LLC (US) 2026-03-17 US disclosed
US-12561392-B2 Relative fuzziness for fast reduction of false positives and false negatives in computational text searches DENNINGHOFF KARL LOUIS (US) 2026-02-24 US disclosed
EP-4290372-B1 FUNCTION CALLING CONTEXT ENCODING METHOD AND APPARATUS, AND FUNCTION CALLING CONTEXT DECODING METHOD AND APPARATUS HUAWEI TECH CO LTD (CN) 2025-12-24 EP disclosed
US-20250371079-A1 CLASSIFYING DOCUMENTS USING A DOMAIN-SPECIFIC NATURAL LANGUAGE PROCESSING MODEL BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-04 US disclosed
US-12443575-B1 Systems and methods for validation of data entries for user interface data sets JASE MEDICAL L.L.C. (US) 2025-10-14 US disclosed
EP-1505968-A1 MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES ELI LILLY AND COMPANY (US) 2005-02-16 EP disclosed
WO-2003097047-A1 MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES ELI LILLY AND COMPANY (US) 2003-11-27 WO disclosed
US-6201119-B1 2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-9-AMINE COMPOUNDS USEFUL AS INTERMEDIATES TO ANTIVIRALS JANSSEN PHARMACEUTICA N.V. (BE) 2001-03-13 US disclosed
CN-1193276-A Use of oxido-squalene cyclase inhibitors for lowering cholesterol in blood ZENECA LTD (GB) 1998-09-16 CN disclosed
US-5371079-A Administering to inhibit replication of HIV-1 in human cells JANSSEN PHARMACEUTICA N.V. (BE) 1994-12-06 US disclosed
US-5270464-A Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones JANSSEN PHARMACEUTICA N.V. (BE) 1993-12-14 US disclosed
US-3937699-A BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12561392-B2 Relative fuzziness for fast reduction of false positives and false negatives in computational text searches SET, FASTKD5, CPSF6 TDP1 2395/4885ELANE 3799/4885DGAT1 4801/4885
US-12579594-B1 Systems and methods for dynamically updating data for course generation STAT4, STAT1, DDX5 TDP1 340/4885ELANE 1137/4885DGAT1 3787/4885
US-20260147459-A1 SYSTEMS AND METHODS FOR DYNAMIC USER INTERFACE INTERACTIONS EPHA7, EPHA6, EPHA8 TDP1 972/4885ELANE 3087/4885DGAT1 3870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.