SCHEMBL449500

SCHEMBL449500

C=Cc1ccc(C(C)(O)CC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TAS1R3 Q7RTX0 2/20 0.39
TAS1R1 Q7RTX1 2/20 0.39
TDP1 Q9NUW8 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
TSHR P16473 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AOC3 Q16853 1/20 0.32
TRPA1 O75762 1/20 0.32
NR1H2 P55055 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124305 0.86 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1TDP1CHRNB2
SCHEMBL7574539 0.82 ESR1 (0.44) TSHRESR1ESR2MAPTLMNA
SCHEMBL9580960 0.82 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1TDP1CHRNB2
SCHEMBL4895391 0.82 ESR1 (0.41) ALDH1A1TAS1R3TAS1R1TDP1CHRNB2
SCHEMBL123079 0.80 TAS1R3 (0.38) ALDH1A1TAS1R3TAS1R1ESR1ESR2
Styrene SCHEMBL27456644 0.80 ALDH1A1 (0.47) ALDH1A1TAS1R3TAS1R1TSHRESR1
SCHEMBL24741222 0.80 ALDH1A1 (0.33) ALDH1A1TAS1R3TAS1R1
SCHEMBL26099043 0.79 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1TDP1CHRNB2
SCHEMBL4272691 0.79 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL452090 0.79 ALDH1A1 (0.52) ALDH1A1TAS1R3TAS1R1TDP1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4748806-B2 2011-08-17 JP claimed
CN-101253427-B Multilayer optical compensator NITTO DENKO CORP 2010-05-26 CN claimed
CN-100538476-C Multilayer optical compensation film EASTMAN KODAK CO (JP) 2009-09-09 CN claimed
CN-100416680-C Optical multilayer EASTMAN KODAK CO (JP) 2008-09-03 CN claimed
CN-101253427-A Multilayer optical compensator EASTMAN KODAK CO (JP) 2008-08-27 CN claimed
US-7288296-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-10-30 US claimed
US-7250200-B2 Liquid crystal cell with compensator layer and process NITTO DENKO CORPORATION (JP) 2007-07-31 US claimed
US-7236221-B2 Multilayer optical compensation film, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-06-26 US claimed
CN-1973242-A Multilayer optical compensation film EASTMAN KODAK CO (JP) 2007-05-30 CN claimed
CN-1961229-A Multilayered optical compensator film with amorphous polymer for liquid crystal displays EASTMAN KODAK CO (US) 2007-05-09 CN claimed
US-7211316-B2 Optical multilayer NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
US-7157736-B2 Multi-layer compensation film including stretchable barrier layers EASTMAN KODAK COMPANY (US) 2007-01-02 US claimed
CN-1875413-A Optical multilayer EASTMAN KODAK CO (US) 2006-12-06 CN claimed
US-20050286001-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-29 US claimed
US-20050270458-A1 Multilayer optical compensation film, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050270459-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050237457-A1 Multi-layer compensation film including stretchable barrier layers EASTMAN KODAK COMPANY 2005-10-27 US claimed
WO-2005045820-A1 OPTICAL MULTILAYER EASTMAN KODAK COMPANY (US) 2005-05-19 WO claimed
US-20050089676-A1 Optical multilayer EASTMAN KODAK COMPANY 2005-04-28 US claimed
US-20040223103-A1 Liquid crystal cell with compensator layer and process EASTMAN KODAK COMPANY 2004-11-11 US claimed