Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124305 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TAS1R3TAS1R1TDP1TSHR | |
| SCHEMBL449500 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TAS1R3TAS1R1TDP1TSHR | |
| SCHEMBL4895391 | 0.80 | ESR1 (0.41) | ALDH1A1TAS1R3TAS1R1TDP1CYP1A2 | |
| Styrene SCHEMBL27456644 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TAS1R3TAS1R1TSHRMAPT | |
| SCHEMBL123079 | 0.79 | TAS1R3 (0.38) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL452090 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TAS1R3TAS1R1TDP1TSHR | |
| SCHEMBL24741222 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL17445916 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TAS1R3TAS1R1TDP1TSHR | |
| SCHEMBL6838055 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TAS1R3TAS1R1TDP1TSHR | |
| SCHEMBL20543582 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TAS1R3TAS1R1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210148-A | Styrenic polymer containing polyisobutylene side-chains | UNIVERSITY OF OTTAWA (CA) | 1993-05-11 | — | — | US | disclosed |