SCHEMBL452090

SCHEMBL452090

C=Cc1ccc(C(C)(C)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 2/20 0.40
HDAC8 Q9BY41 1/20 0.39
CYP1A2 P05177 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
TRPA1 O75762 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD11B1 P28845 1/20 0.34
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445916 0.82 ALDH1A1 (0.48) ALDH1A1TDP1TSHRHDAC8CYP1A2
SCHEMBL6838055 0.82 ALDH1A1 (0.48) ALDH1A1TDP1TSHRHDAC8CYP1A2
SCHEMBL1024017 0.80 ALDH1A1 (0.58) ALDH1A1TDP1TSHRHDAC8CYP1A2
SCHEMBL15198 0.80 ALDH1A1 (0.58) ALDH1A1TDP1TSHRHDAC8CYP1A2
SCHEMBL196799 0.79 MEN1 (0.48) ALDH1A1TDP1TSHRMEN1KMT2A
SCHEMBL29066407 0.79 ALDH1A1 (0.50) ALDH1A1TDP1TSHRHDAC8MEN1
SCHEMBL5402087 0.79 HSD11B1 (0.46) ALDH1A1HSD11B1NR1H2NR1H3
SCHEMBL449500 0.79 ALDH1A1 (0.44) ALDH1A1TDP1TSHRHDAC8CYP1A2
Hydrogen Sulfide SCHEMBL29029008 0.78 ALDH1A1 (0.55) ALDH1A1TDP1TSHRHDAC8CYP1A2
SCHEMBL23044786 0.77 ALDH1A1 (0.48) ALDH1A1TDP1TSHRHDAC8CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116265034-A Multifunctional anticoagulation coating and plasma preparation method and application thereof 中国科学院深圳先进技术研究院 2023-06-20 CN claimed
CN-106662810-B Negative resist composition and polyfunctional polymer therein 国际商业机器公司 2020-08-11 CN claimed
US-10345700-B2 Negative-tone resist compositions and multifunctional polymers therein INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-07-09 US claimed
US-20160070169-A1 NEGATIVE-TONE RESIST COMPOSITIONS AND MULTIFUNCTIONAL POLYMERS THEREIN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-03-10 US claimed
CN-101794892-B Polymer electrolyte membrane comprising alkylether graft chain and method of producing same INDEPENDENT ADMINISTRATIVE INSTITUTION JAPAN ATOMIC ENERGY AGENCY 2014-04-09 CN claimed
US-20130288159-A1 POLYMER ELECTROLYTE MEMBRANE HAVING ALKYLETHER GRAFT CHAIN KANAGAWA UNIVERSITY (JP) 2013-10-31 US claimed
US-8470895-B2 Polymer electrolyte membrane comprising alkylether graft chain and method of producing the same JAPAN ATOMIC ENERGY AGENCY (JP) 2013-06-25 US claimed
US-20100216901-A1 Polymer electrolyte membrane comprising alkylether graft chain and method of producing the same JAPAN ATOMIC ENERGY AGENCY (JP) 2010-08-26 US claimed
CN-101794892-A The polyelectrolyte membrane and the manufacture method thereof that contain alkylether graft chain JAPAN ATOMIC ENERGY AGENCY 2010-08-04 CN claimed
US-12164227-B2 Chemically amplified negative resist composition and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-12-10 US disclosed
EP-4459376-A2 ALCOHOL COMPOUND, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2024-11-06 EP disclosed
CN-114924463-B Chemically amplified negative resist composition and resist pattern forming method 信越化学工业株式会社 2024-09-24 CN disclosed
US-20240215891-A1 Bio-Electrode Composition, Bio-Electrode, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20240215891-A1 Bio-Electrode Composition, Bio-Electrode, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-5214105-A Preparation of graft copolymers from macromolecules containing reactive tertiary structures UNIVERSITY OF OTTAWA (CA) 1993-05-25 US disclosed
US-5210148-A Styrenic polymer containing polyisobutylene side-chains UNIVERSITY OF OTTAWA (CA) 1993-05-11 US disclosed
US-5084522-A Styrenic polymer containing pendant reactive tertiary structures and the preparation thereof UNIVERSITY OF OTTAWA (CA) 1992-01-28 US disclosed
EP-0201827-B1 ELECTROVISCOUS FLUIDS BAYER AG (DE) 1989-11-08 EP disclosed
EP-0096647-B1 A METHOD FOR PREPARING A POLYMER CONTAINING PENDANT UNSATURATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-10-29 EP disclosed
US-4446284-A Method for preparing a polymer containing pendant unsaturation THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-05-01 US disclosed