Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495521 | 1.00 | KMT2A (0.56) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL2397463 | 0.76 | KMT2A (0.58) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL29793869 | 0.75 | KMT2A (0.55) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL21788603 | 0.75 | KMT2A (0.55) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL4495517 | 0.75 | KMT2A (0.53) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL4495511 | 0.75 | KMT2A (0.53) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL25062632 | 0.75 | CYP2A6 (0.57) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL13600942 | 0.73 | MAPT (0.53) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL4495518 | 0.73 | MAPT (0.53) | KMT2AALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL11354104 | 0.73 | LMNA (0.55) | KMT2AALDH1A1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | KMT2A 312/4885ALDH1A1 658/4885ADORA2A 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.