SCHEMBL4495518

SCHEMBL4495518

CC=CC(=O)NC(C)c1cc2cccc(OC)c2o1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
LMNA P02545 2/20 0.49
RECQL P46063 1/20 0.49
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13600942 1.00 MAPT (0.53) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4504081 0.86 KMT2A (0.53) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4504074 0.86 KMT2A (0.53) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4518064 0.85 CNR2 (0.48) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4518068 0.85 CNR2 (0.48) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4503151 0.84 LMNA (0.58) MAPTKMT2AMEN1LMNARECQL
SCHEMBL13601005 0.77 ALDH1A1 (0.48) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL4495521 0.73 KMT2A (0.56) MAPTKMT2AMEN1LMNARECQL
SCHEMBL4495508 0.73 KMT2A (0.56) MAPTKMT2AMEN1LMNARECQL
SCHEMBL25062632 0.73 CYP2A6 (0.57) MAPTKMT2AMEN1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638540-B2 Benzofuran compound and medicinal composition containing the same THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) 2009-12-29 US disclosed
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) 2006-08-31 US disclosed
EP-1627873-A1 BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME The New Industry Research Organization (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same LTB4R2, LTC4S, LTB4R MAPT 1497/4885KMT2A 312/4885MEN1 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.