Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.51 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.50 |
| ▸ | PFKFB2 | O60825 | 2/20 | 0.50 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449568 | 1.00 | SCN3A (0.52) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL23373349 | 0.92 | PFKFB3 (0.54) | SCN3ASCN9APSMB8PFKFB1PFKFB3 | |
| SCHEMBL10327297 | 0.84 | SCN3A (0.55) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL24609551 | 0.84 | SCN3A (0.55) | SCN3ASCN9APSMB8PFKFB1PFKFB3 | |
| SCHEMBL873241 | 0.84 | SCN3A (0.55) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL17676974 | 0.84 | SCN3A (0.55) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL13388756 | 0.83 | SCN3A (0.64) | SCN3ASCN9APSMB8ULK1SCN5A | |
| SCHEMBL7692273 | 0.82 | SCN3A (0.56) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL29365790 | 0.82 | SCN3A (0.56) | SCN3ASCN9AEPHX1PSMB8PFKFB1 | |
| SCHEMBL13379539 | 0.81 | SCN3A (0.58) | SCN3ASCN9AEPHX1PSMB8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431353-B1 | Process for preparing amine compound | KANTO KAGAKU (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2431353-A1 | Process for preparing amine compound | Kanto Kagaku Kabushiki Kaisha (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065426-A1 | PROCESS FOR PREPARING AMINE COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065426-A1 | PROCESS FOR PREPARING AMINE COMPOUND | PNMT, HNMT, GNMT | SCN3A 4119/4885SCN9A 2433/4885EPHX1 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.