Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12414224 | 0.71 | PKM (0.42) | — | |
| SCHEMBL4491773 | 0.65 | IDH1 (0.40) | RAB9A | |
| SCHEMBL4497189 | 0.64 | GALR3 (0.38) | RAB9A | |
| SCHEMBL30562904 | 0.62 | PDE4A (0.41) | — | |
| SCHEMBL21456839 | 0.62 | PDE4A (0.41) | — | |
| SCHEMBL2621720 | 0.62 | PDE4A (0.41) | — | |
| SCHEMBL24669962 | 0.60 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL3234702 | 0.59 | CA1 (0.42) | NPC1RAB9A | |
| SCHEMBL23862938 | 0.59 | AURKA (0.55) | — | |
| SCHEMBL505780 | 0.59 | KDM1A (0.48) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222261-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2012-07-17 | — | — | US | disclosed |
| US-20090318477-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318477-A1 | CHEMICAL COMPOUNDS | GPR119, GOT2, SLC5A2 | NPC1 232/4885RAB9A 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.