Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832886 | 0.83 | HTT (0.46) | NR4A2DYRK1AKDM4EALDH1A1HTT | |
| SCHEMBL4522163 | 0.79 | PARP1 (0.41) | NR4A2DYRK1AKDM4EHTTLRRK2 | |
| SCHEMBL28906978 | 0.79 | KDM4E (0.54) | KDM4ESMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL13977561 | 0.79 | PSMD14 (0.56) | NR4A2DYRK1AKDM4EALDH1A1HTT | |
| SCHEMBL5759312 | 0.79 | HTR1A (0.51) | KDM4EALDH1A1SMN1; SMN2HTTLRRK2 | |
| SCHEMBL317372 | 0.79 | KDM4E (0.49) | NR4A2DYRK1AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30492608 | 0.78 | CCR1 (0.45) | KDM4EALDH1A1HTTLRRK2PIM1 | |
| SCHEMBL25216590 | 0.78 | CCR1 (0.45) | KDM4EALDH1A1HTTLRRK2PIM1 | |
| SCHEMBL7460554 | 0.78 | NR4A2 (0.44) | NR4A2DYRK1AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL318769 | 0.77 | NR4A2 (0.68) | NR4A2DYRK1AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101443313-A | Quinoline derivatives and their use as pesticides | BASF SE (DE) | 2009-05-27 | — | — | CN | disclosed |
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | BASF SE (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-2007727-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007104726-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | CBR3, HCRTR1, HCAR3 | NR4A2 480/4885DYRK1A 2143/4885KDM4E 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.