Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507444 | 0.88 | PDE4D (0.39) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL4500314 | 0.85 | ALDH1A1 (0.34) | ROCK2ROCK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4501160 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2HTTPOLBHPGDALDH1A1 | |
| SCHEMBL6448509 | 0.83 | PKM (0.39) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL10729447 | 0.83 | HTT (0.34) | SMN1; SMN2FGFR1KDRKMT2AHTT | |
| SCHEMBL10724382 | 0.80 | PKM (0.34) | SMN1; SMN2FGFR1KDRKMT2AMEN1 | |
| SCHEMBL8423375 | 0.79 | FGFR1 (0.34) | SMN1; SMN2FGFR1KDRKMT2AHTT | |
| SCHEMBL9076331 | 0.78 | KDM4E (0.38) | KMT2AMEN1HPGDALDH1A1CYP1A2 | |
| SCHEMBL22945925 | 0.77 | CNR1 (0.33) | SMN1; SMN2KMT2AHTTPOLBALDH1A1 | |
| SCHEMBL10755351 | 0.76 | POLB (0.46) | SMN1; SMN2KMT2AMEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635664-B2 | Herbicidal substituted benzoylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20040110640-A1 | Herbicidal substituted benzoylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110640-A1 | Herbicidal substituted benzoylpyrazoles | DDT, GLRX3, CBR3 | SMN1; SMN2 4258/4885CDC7 2929/4885PLK4 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.