Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31132806 | 0.82 | TEK (0.60) | ABL1KDM4ECDK8 | |
| SCHEMBL30473406 | 0.82 | HSD17B10 (0.49) | ABL1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24932100 | 0.82 | ALDH1A1 (0.55) | ABL1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31132621 | 0.81 | ABL1 (0.44) | ABL1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15348810 | 0.81 | KDM4E (0.54) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL24298066 | 0.80 | FFAR2 (0.45) | ABL1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31132794 | 0.77 | ALDH1A1 (0.47) | ABL1KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4074720 | 0.77 | DEGS1 (0.55) | RAB9ANPC1KMT2AMEN1GRM5 | |
| SCHEMBL18795091 | 0.76 | TEK (0.49) | ABL1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16058723 | 0.76 | GRM5 (0.48) | RAB9ANPC1KMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | ABL1 920/4885KDM4E 249/4885RAB9A 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.