Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586405 | 0.92 | THRB (0.42) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7067550 | 0.86 | THRA (0.40) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL3177108 | 0.84 | THRA (0.38) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7067194 | 0.82 | THRA (0.50) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL8897387 | 0.81 | AKR1B1 (0.43) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7066894 | 0.81 | THRA (0.41) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7065792 | 0.81 | THRA (0.41) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL453710 | 0.80 | HTR1B (0.52) | KDM4EMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL7067884 | 0.79 | THRB (0.40) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7063664 | 0.79 | THRA (0.52) | THRATHRBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | claimed |
| US-8778636-B2 | Chemo-enzymatic approach to the synthesis of pimecrolimus | EUTICALS S.P.A. (IT) | 2014-07-15 | — | — | US | disclosed |
| US-20120064575-A1 | CHEMO-ENZYMATIC APPROACH TO THE SYNTHESIS OF PIMECROLIMUS | AMRI ITALY S.R.L. (IT) | 2012-03-15 | — | — | US | disclosed |
| US-7849022-B2 | Optical functional sheet, and display device | FUJIFILM CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080013341-A1 | OPTICAL FUNCTIONAL SHEET, AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2008-01-17 | — | — | US | disclosed |
| US-20030096172-A1 | Hologram recording material composition and hologram recording medium | DAISO CO., LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-0530082-B1 | Curable composition for use in optical fiber cladding and optical fiber equipped therewith | DAINIPPON INK & CHEMICALS (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5333234-A | Curable composition for use in optical fiber cladding and optical fiber equipped therewith | DAINIPPON INK AND CHEMCIALS, INC. (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0530082-A1 | Curable composition for use in optical fiber cladding and optical fiber equipped therewith | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4829101-A | SHELL-CORE POLYMERS | ROHM GMBH (DE) | 1989-05-09 | — | — | US | disclosed |
| US-4806348-A | Method for inducing antibody formation | ROHM GMBH (DE) | 1989-02-21 | — | — | US | disclosed |
| US-4710525-A | SHELL-CORE | ROHM GMBH (DE) | 1987-12-01 | — | — | US | disclosed |
| US-4059545-A | Crosslinked styrene polymer foam having suppressed ignition properties | THE DOW CHEMICAL COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064575-A1 | CHEMO-ENZYMATIC APPROACH TO THE SYNTHESIS OF PIMECROLIMUS | CYP51A1, PIM1, COASY | THRA 4683/4885THRB 4681/4885KDM4E 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.