Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.41 |
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065792 | 1.00 | THRA (0.41) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7067550 | 0.95 | THRA (0.40) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7067884 | 0.91 | THRB (0.40) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL449703 | 0.81 | THRA (0.44) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL1805856 | 0.81 | TSHR (0.44) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7065789 | 0.80 | THRA (0.39) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL1535013 | 0.79 | GABRA1 (0.37) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL4646137 | 0.79 | GABRA1 (0.41) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL3742121 | 0.78 | TSHR (0.46) | THRATHRBKDM4EMEN1KMT2A | |
| SCHEMBL7063664 | 0.78 | THRA (0.52) | THRATHRBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |