Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496742 | 0.85 | CCR1 (0.36) | — | |
| SCHEMBL4492959 | 0.75 | CA12 (0.41) | PTGES | |
| SCHEMBL4491011 | 0.75 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL4488177 | 0.74 | BTK (0.41) | BTKPTGES | |
| SCHEMBL4504198 | 0.72 | LDHA (0.38) | — | |
| SCHEMBL4495798 | 0.72 | ERN1 (0.46) | — | |
| SCHEMBL4498684 | 0.72 | CSNK1D (0.44) | — | |
| SCHEMBL4488655 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL4491755 | 0.70 | TRPV1 (0.36) | DHODH | |
| SCHEMBL4492341 | 0.67 | LDHA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |