SCHEMBL449825

SCHEMBL449825

CCc1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.52
RAB9A P51151 1/20 0.45
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
LTA4H P09960 4/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.39
APP P05067 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866672 0.91 SMN1; SMN2 (0.44) TP53RAB9ACYP1A2CYP2A6RXRA
SCHEMBL446441 0.84 THRB (0.42) LTA4H
SCHEMBL1021217 0.81 LTA4H (0.46) LTA4H
SCHEMBL23260597 0.80 LTA4H (0.61) TP53RAB9APPARGPPARALTA4H
Alcohol SCHEMBL29217393 0.80 ALDH1A1 (0.43) TP53LTA4HLMNAL3MBTL1
SCHEMBL172238 0.80 LTA4H (0.61) TP53RAB9APPARGPPARALTA4H
SCHEMBL13289 0.79 LTA4H (0.50) LTA4HLMNAAPPL3MBTL1
SCHEMBL28017927 0.79 LTA4H (0.50) LTA4HLMNAAPPL3MBTL1
SCHEMBL20445675 0.78 MAOA (0.48) RAB9APPARGPPARALTA4H
Hexane SCHEMBL28730435 0.78 LTA4H (0.52) LTA4HSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
WO-2020131441-A1 GREASE COMPOSITIONS HAVING IMPROVED PERFORMANCE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
EP-2038385-A1 NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
US-20080207475-A1 High viscosity novel base stock lubricant viscosity blends HAIGH HEATHER M 2008-08-28 US disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145923-A1 NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed