SCHEMBL449837

SCHEMBL449837

CC(=O)N(C)[Si](C)(N(C)C(C)=O)N(C)C(C)=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202677 0.80 LMNA (0.31) LMNAALDH1A1TSHR
SCHEMBL537585 0.80
SCHEMBL508215 0.79 LMNA (0.36) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL31114683 0.71 ALDH1A1 (0.32) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL452932 0.71 ALDH1A1 (0.32) ALDH1A1
SCHEMBL451522 0.71 ALDH1A1 (0.32) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL8315504 0.71
SCHEMBL9635607 0.69 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11124743 0.69
SCHEMBL24436900 0.69 CHRM2 (0.31) CHRM1CHRM2CHRM4CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US claimed
US-9663621-B2 Moisture curable compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013090127-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013090132-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US claimed
WO-2012033886-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-15 WO claimed
US-6451440-B2 MOISTURE-CURABLE POLYSILOXANE COMPONENT COMPRISING A MIXTURE OR REACTION PRODUCT OF A HYDROLYZABLE POLYSILOXANE POLYMER AND A POLYFUNCTIONAL SILICON COMPOUND; CYCLIC PARAFFINIC HYDROCARBON FLUID GENERAL ELECTRIC COMPANY 2002-09-17 US claimed
US-20010049427-A1 Room temperature curable silicone sealant MOMENTIVE PERFORMANCE MATERIALS INC. 2001-12-06 US claimed
US-4477606-A Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same TORAY SILICONE CO., LTD. (JP) 1984-10-16 US claimed