⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000666 | 0.83 | POLB (0.32) | — | |
| SCHEMBL202677 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL449837 | 0.80 | CHRM1 (0.35) | — | |
| SCHEMBL508215 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL5068318 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL3458095 | 0.73 | — | — | |
| SCHEMBL452932 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL451522 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL8315504 | 0.71 | — | — | |
| SCHEMBL31114683 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 771 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748846-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT | GUANGZHOU MEDICAL UNIVERSITY (CN) | 2026-05-27 | — | — | EP | claimed |
| CN-122080117-A | Preparation method of N-fluorenylmethoxycarbonyl-O-tert-butyl-L-threonine-phenylalanine | — | 2026-05-26 | — | — | CN | claimed |
| EP-4703369-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY USING TEMPORARILY PROTECTED AMINO ACIDS AS AMINE COMPONENTS | GUANGZHOU MEDICAL UNIVERSITY (CN) | 2026-03-04 | — | — | EP | claimed |
| US-20260001906-A1 | Method for Synthesizing Amide and/or Polypeptide Using Temporary Protected Amino Acid as Ammonia Component | UNIV GUANGZHOU MEDICAL (CN) | 2026-01-01 | — | — | US | claimed |
| US-20260001907-A1 | Method for Synthesizing Amide and/or Polypeptide Using Transient Protected Amino Acid as Ammonia Component | UNIV GUANGZHOU MEDICAL (CN) | 2026-01-01 | — | — | US | claimed |
| US-12297172-B2 | Compositions of trofinetide | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2025-05-13 | — | — | US | claimed |
| WO-2025078040-A1 | LYSINE SALT AND METHOD OF MANUFACTURING A LYSINE DERIVATIVE | BACHEM HOLDING AG (CH) | 2025-04-17 | — | — | WO | claimed |
| CN-119371478-A | Method for synthesizing amide and/or polypeptide by taking transient protection amino acid as ammonia component | 广州医科大学 | 2025-01-28 | — | — | CN | claimed |
| WO-2025015659-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT | 广州医科大学 | 2025-01-23 | — | — | WO | claimed |
| CN-119306763-A | Synthesis method of ceftaroline fosamil diphosphate U2 impurity reference substance | 暨明医药科技（苏州）有限公司 | 2025-01-14 | — | — | CN | claimed |
| EP-0169144-B1 | PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES | GEMA S.A. (ES) | 1990-06-06 | — | — | EP | claimed |
| US-4782040-A | Porous materials having a dual surface | DOW CORNING CORPORATION (US) | 1988-11-01 | — | — | US | claimed |
| US-4670059-A | Increased solubility of carbon black | HEWLETT PACKARD COMPANY (US) | 1987-06-02 | — | — | US | claimed |
| EP-0169144-A2 | Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins from the corresponding 6-substituted amino penicillin sulphoxides | GEMA S.A. (ES) | 1986-01-22 | — | — | EP | claimed |
| EP-0034394-B1 | PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1984-08-01 | — | — | EP | claimed |
| US-4366315-A | Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds | GIST-BROCADES N.V. (NL) | 1982-12-28 | — | — | US | claimed |
| EP-0034394-A2 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1981-08-26 | — | — | EP | claimed |
| US-4029883-A | Dehydroxylation of aminosugars | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-06-14 | — | — | US | claimed |
| US-4020269-A | Epiminodeaminodeoxyaminoglycoside antibiotics and intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-04-26 | — | — | US | claimed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | claimed |