Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30960769 | 0.77 | MET (0.47) | MEN1HPGDKMT2AHSD17B10MET | |
| SCHEMBL3865471 | 0.73 | MET (0.43) | MEN1HPGDKMT2AHSD17B10MET | |
| SCHEMBL3870912 | 0.72 | MET (0.43) | MEN1HPGDKMT2AHSD17B10MET | |
| SCHEMBL3864918 | 0.72 | MET (0.43) | MEN1HPGDKMT2AHSD17B10MET | |
| SCHEMBL28496119 | 0.70 | GPBAR1 (0.44) | MEN1HPGDKMT2AHSD17B10MET | |
| SCHEMBL976184 | 0.70 | MEN1 (0.41) | MEN1HPGDKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL976183 | 0.70 | MEN1 (0.41) | MEN1HPGDKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL15540388 | 0.69 | MEN1 (1.00) | MEN1HPGDKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3304570 | 0.69 | MEN1 (1.00) | MEN1HPGDKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL15539513 | 0.69 | MEN1 (1.00) | MEN1HPGDKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023724-A1 | Heteroaryl compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC | 2009-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023724-A1 | Heteroaryl compounds, compositions thereof, and methods of treatment therewith | JAK2, PHKG1, PHKG2 | MEN1 3172/4885HPGD 1483/4885KMT2A 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.