Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226652 | 0.80 | ACACB (0.43) | ACACBCA12CA1CA2CA7 | |
| SCHEMBL966608 | 0.80 | AR (0.57) | ARPGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL13117493 | 0.78 | ACACB (0.48) | ACACBCA12CA1CA2CA7 | |
| SCHEMBL987451 | 0.78 | GAA (0.41) | ACACBCA12CA1CA2CA7 | |
| SCHEMBL29007575 | 0.78 | CA12 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3434561 | 0.78 | CA12 (0.56) | ACACBCA12CA1CA2CA7 | |
| SCHEMBL17672656 | 0.77 | ALDH1A1 (0.41) | CA12CA2ARPGRNFE2L2 | |
| SCHEMBL26155371 | 0.77 | ACACB (0.46) | ACACBCA12CA1CA2CA7 | |
| SCHEMBL29641932 | 0.76 | CYP1A2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2720566 | 0.76 | CYP1A2 (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071468-B | Heterocyclic compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-109071468-A | Heterocyclic compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-2694481-B1 | IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER (US) | 2015-12-30 | — | — | EP | disclosed |
| US-8809333-B2 | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-08-19 | — | — | US | disclosed |
| EP-2694481-A1 | IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc (US) | 2014-02-12 | — | — | EP | disclosed |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2012137099-A1 | IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-10-11 | — | — | WO | disclosed |
| US-20090281120-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1961745-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-0579908-B1 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1997-09-10 | — | — | EP | disclosed |
| US-5371095-A | Fungicides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0579908-A2 | Pyridyl derivatives, process for their preparation and their use as pesticides | BAYER AG (DE) | 1994-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281120-A1 | BICYCLIC HETEROCYCLIC COMPOUND | CRHR1, NR3C1, CNR1 | ACACB 3668/4885PDE4A 2861/4885PDE4B 2915/4885 |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | AADAC, TPX2, NLRP3 | ACACB 2320/4885PDE4A 3153/4885PDE4B 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.