SCHEMBL449946

SCHEMBL449946

C/C(=N/O)C(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 11/20 0.60
CES1 P23141 10/20 0.60
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.47
CYP2C19 P33261 1/20 0.47
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
GLA P06280 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.45
XBP1 P17861 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
DAO P14920 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108031 1.00 CES2 (0.60) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL28138711 1.00 CES2 (0.60) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL1049892 1.00 CES2 (0.60) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11488533 0.88 SMN1; SMN2 (0.59) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11373661 0.88 SMN1; SMN2 (0.59) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11373666 0.88 SMN1; SMN2 (0.59) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11424490 0.85 CES2 (0.54) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11714645 0.83 PARP10 (0.53) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL11714663 0.83 PARP10 (0.53) CES2CES1MAPTSMN1; SMN2POLB
SCHEMBL28543716 0.82 CES2 (0.50) CES2CES1MAPTSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240168374-A1 PHOTORESIST COMPOSITION TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2024-05-23 US claimed
CN-117142982-A Synthesis method of 2-iso-nitrosopropiophenone 沈阳思拓新材料技术有限公司 2023-12-01 CN claimed
EP-3379248-B1 ARGINASE ACTIVITY MEASUREMENT METHOD, ARGINASE ACTIVITY DETECTION KIT, ARGINASE-RELATED DISEASE DETECTION KIT, AND ARGINASE INHIBITOR OR ACTIVE AGENT SCREENING METHOD TOKYO OHKA KOGYO CO LTD (JP) 2020-09-23 EP claimed
EP-3379248-A1 ARGINASE ACTIVITY MEASUREMENT METHOD, ARGINASE ACTIVITY DETECTION KIT, ARGINASE-RELATED DISEASE DETECTION KIT, AND ARGINASE INHIBITOR OR ACTIVE AGENT SCREENING METHOD Tokyo Ohka Kogyo Co., Ltd. (JP) 2018-09-26 EP claimed
JP-58039648-A None JP disclosed
JP-57126451-A None JP disclosed
JP-3193767-A None JP disclosed
US-12638708-B2 Method for manufacturing display device JAPAN DISPLAY INC. (JP) 2026-05-26 US disclosed
WO-2026105567-A1 BRANCHED ORGANOPOLYSILOXANE, CURABLE COMPOSITION, AND USE THEREOF ダウ・東レ株式会社 2026-05-21 WO disclosed
WO-2026105566-A1 BRANCHED ORGANOPOLYSILOXANE, CURABLE COMPOSITION, AND USE THEREOF ダウ・東レ株式会社 2026-05-21 WO disclosed
CN-122037081-A Active energy ray-curable composition, cured product, and laminate 荒川化学工业株式会社 2026-05-15 CN disclosed
US-12624174-B2 Hydrogen-bond enriched ion exchange membranes THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2026-05-12 US disclosed
US-4224246-A Process for the synthesis and separation of the threo and erythro isomers of 2-amino-1-phenyl-1-propanol INTERNATIONAL MINERALS AND CHEMICAL CORPORATION (US) 1980-09-23 US disclosed
US-4198421-A ANTIARTHRITIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed
EP-0005172-A1 Coumarin derivatives and their use as brightening agents for high molecular organic substances BAYER AG (DE) 1979-11-14 EP disclosed
US-4144243-A OPTICAL BRIGHTENERS FOR TEXTILES AND LACQUEARS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4006158-A Fluorescent 1,2,3-triazole derivatives of 3-phenylcoumarin SANDOZ LTD. (CH) 1977-02-01 US disclosed
US-4005098-A BRIGHTENING AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US disclosed
US-3965094-A Process for the manufacture of 2-aryl-v-triazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-22 US disclosed
US-3947412-A CYCLIZATION IN THE PRESENCE OF HEAVY METALS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638708-B2 Method for manufacturing display device GJB2, PDCD2L, VCL CES2 959/4885CES1 3297/4885MAPT 254/4885
US-12624174-B2 Hydrogen-bond enriched ion exchange membranes SLC9A2, SLC9A3, SLC9A1 CES2 1474/4885CES1 4082/4885MAPT 3413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.