SCHEMBL4499514

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14622471	0.75	CA2 (0.67)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL8933506	0.73	CA2 (0.30)	CA2DDB1CRBN
	SCHEMBL6381006	0.66	KDM4E (0.45)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL16469006	0.66	CA2 (0.58)	CA2GAAMAPTDDB1CRBN
	SCHEMBL15421725	0.64	CA2 (0.47)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL11336562	0.63	TSHR (0.39)	KMT2AMEN1GAAMAPTDDB1
	SCHEMBL11566163	0.63	TDP1 (0.52)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL6277589	0.63	TDP1 (0.52)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL9227199	0.63	MEN1 (0.52)	CA2KMT2AMEN1GAAMAPT
	SCHEMBL9818019	0.62	IDO1 (0.61)	DDB1CRBNALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.