Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517687 | 0.85 | MAPT (0.63) | MRGPRX4MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL4499573 | 0.85 | MRGPRX4 (0.53) | MRGPRX4MAPTNPC1RAB9AGABRA1 | |
| SCHEMBL4505947 | 0.84 | MRGPRX4 (0.55) | MRGPRX4MAPTALDH1A1KMT2A | |
| SCHEMBL4512326 | 0.83 | MRGPRX4 (0.63) | MRGPRX4NPC1RAB9AKDM5AKDM4C | |
| SCHEMBL4504246 | 0.82 | MRGPRX4 (0.56) | MRGPRX4MAPTNPC1RAB9AKDM4C | |
| SCHEMBL4501976 | 0.80 | MRGPRX4 (0.55) | MRGPRX4MAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL4492301 | 0.77 | MRGPRX4 (0.50) | MRGPRX4MAPTNPC1RAB9AGABRA2 | |
| SCHEMBL4499409 | 0.76 | MRGPRX4 (0.63) | MRGPRX4MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2935704 | 0.76 | CYP1A2 (0.49) | MAPTNPC1RAB9AGABRA1GABRG2 | |
| SCHEMBL2010235 | 0.75 | GYS1 (0.54) | MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | MRGPRX4 1550/4885MAPT 4022/4885NPC1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.