Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 10/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508058 | 0.86 | MAOB (0.51) | MAOBNR4A2MAOAGABRA1GABRG2 | |
| SCHEMBL4500448 | 0.84 | NR4A2 (0.61) | MRGPRX4MAOBNR4A2MAOAPARP10 | |
| SCHEMBL4499558 | 0.80 | MRGPRX4 (0.50) | MRGPRX4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4504246 | 0.79 | MRGPRX4 (0.56) | MRGPRX4CYP1A2MAPT | |
| SCHEMBL16872244 | 0.79 | CYP1A2 (0.50) | KDM4EGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15932302 | 0.79 | RAB9A (0.53) | MRGPRX4KDM4EMAPT | |
| SCHEMBL4513766 | 0.76 | MAPT (0.48) | MRGPRX4MAOBKDM4ECYP1A2FFAR1 | |
| SCHEMBL10552186 | 0.75 | MRGPRX4 (0.50) | MRGPRX4MAOBNR4A2KDM4EMAOA | |
| SCHEMBL2935704 | 0.75 | CYP1A2 (0.49) | KDM4EGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4517687 | 0.75 | MAPT (0.63) | MRGPRX4KDM4ECYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | MRGPRX4 1550/4885MAOB 457/4885NR4A2 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.