SCHEMBL449989

SCHEMBL449989

C=Cc1cccc(-c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.60
ALDH1A1 P00352 3/20 0.56
TSHR P16473 1/20 0.56
TP53 P04637 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
TRIM24 O15164 1/20 0.47
TRIM33 Q9UPN9 1/20 0.47
MAOA P21397 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX5 P09917 1/20 0.41
KCNH2 Q12809 1/20 0.41
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41
HDAC2 Q92769 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714226 0.98 ALDH1A1 (0.59) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL30618844 0.98 ALDH1A1 (0.59) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL595152 0.96 ALDH1A1 (0.58) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL8757855 0.95 ALDH1A1 (0.56) PTGS2ALDH1A1TSHRTP53TDP1
Styrene SCHEMBL9129912 0.95 ALDH1A1 (0.64) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL595061 0.95 PTGS2 (0.59) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL2095987 0.91 PTGS2 (0.56) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL4257518 0.91 PTGS2 (0.56) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL29870364 0.91 PTGS2 (0.56) PTGS2ALDH1A1TSHRTP53TDP1
SCHEMBL585196 0.91 TP53 (0.58) PTGS2ALDH1A1TSHRTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794015-B2 2011-10-12 JP claimed
JP-4748806-B2 2011-08-17 JP claimed
US-7288296-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-10-30 US claimed
US-7250200-B2 Liquid crystal cell with compensator layer and process NITTO DENKO CORPORATION (JP) 2007-07-31 US claimed
US-7236221-B2 Multilayer optical compensation film, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-06-26 US claimed
US-7211304-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
US-7211316-B2 Optical multilayer NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
WO-2007001999-A1 MULTILAYERED OPTICAL COMPENSATOR NITTO DENKO CORPORATION (JP) 2007-01-04 WO claimed
US-7157736-B2 Multi-layer compensation film including stretchable barrier layers EASTMAN KODAK COMPANY (US) 2007-01-02 US claimed
US-7031589-B2 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA (US) 2006-04-18 US claimed
US-20050286001-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-29 US claimed
WO-2005121880-A1 MULTILAYER OPTICAL COMPENSATION FILM EASTMAN KODAK COMPANY (US) 2005-12-22 WO claimed
WO-2005121848-A1 MULTILAYERED OPTICAL COMPENSATOR FILM WITH AMORPHOUS POLYMER FOR LIQUID CRYSTAL DISPLAYS NITTO DENKO CORPORATION (JP) 2005-12-22 WO claimed
US-20050270458-A1 Multilayer optical compensation film, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050270459-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050237457-A1 Multi-layer compensation film including stretchable barrier layers EASTMAN KODAK COMPANY 2005-10-27 US claimed
WO-2005045820-A1 OPTICAL MULTILAYER EASTMAN KODAK COMPANY (US) 2005-05-19 WO claimed
US-20050089676-A1 Optical multilayer EASTMAN KODAK COMPANY 2005-04-28 US claimed
US-20040264908-A1 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA, INC. 2004-12-30 US claimed
US-20040223103-A1 Liquid crystal cell with compensator layer and process EASTMAN KODAK COMPANY 2004-11-11 US claimed