SCHEMBL714226

SCHEMBL714226

C=Cc1cccc(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TSHR P16473 1/20 0.59
PTGS2 P35354 1/20 0.57
TP53 P04637 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAOA P21397 1/20 0.44
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
MGLL Q99685 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KMO O15229 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30618844 1.00 ALDH1A1 (0.59) ALDH1A1TSHRPTGS2TP53TDP1
Styrene SCHEMBL9129912 0.98 ALDH1A1 (0.64) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL449989 0.98 PTGS2 (0.60) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL8757855 0.98 ALDH1A1 (0.56) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL595152 0.94 ALDH1A1 (0.58) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL595061 0.93 PTGS2 (0.59) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL30485440 0.93 TP53 (0.58) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL585196 0.93 TP53 (0.58) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL596121 0.90 TP53 (0.56) ALDH1A1TSHRPTGS2TP53TDP1
SCHEMBL2095987 0.88 PTGS2 (0.56) ALDH1A1TSHRPTGS2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545780-B2 Flexible metal clad laminates and methods of preparation thereof NOTARK CORPORATION (US) 2026-02-10 US claimed
CN-115819649-B Polymerization preparation method of polystyrene derivative 南阳森源塑胶有限公司 2025-06-13 CN claimed
CN-117855600-A Gel polymer electrolyte and application thereof 广州天赐高新材料股份有限公司 2024-04-09 CN claimed
CN-117720787-A Flexible metal clad laminate and method of making the same 科腾聚合物荷兰有限责任公司 2024-03-19 CN claimed
US-20240067810-A1 FLEXIBLE METAL CLAD LAMINATES AND METHODS OF PREPARATION THEREOF Kraton Corporation (US) 2024-02-29 US claimed
US-20240002564-A1 COPOLYMERS OF DIISOALKENYLARENE AND COMPOSITIONS THEREOF Kraton Corporation (US) 2024-01-04 US claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-115819649-A Polymerization preparation method of polystyrene derivative 南阳森源塑胶有限公司 2023-03-21 CN claimed
CN-111205584-B Preparation method of flame-retardant ultraviolet radiation-resistant polycarbonate material 衢州学院 2023-02-17 CN claimed
US-10961383-B2 Gradient block copolymers for directed self-assembly BREWER SCIENCE, INC. (US) 2021-03-30 US claimed
CN-1249153-C Polystyrene reactor alloy with high impact resistance SAMSUNG GENERAL CHEMICALS CO (KR) 2006-04-05 CN claimed
EP-1311612-A4 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG ATOFINA CO LTD (KR) 2005-04-06 EP claimed
US-6780938-B2 IN COMPARISON WITH A MELT BLEND WITHOUT IMPAIRING HEAT RESISTANCE AND ELASTIC MODULUS BY INTRODUCING RUBBERY ELASTOMER AND POLYPHENYLENE ETHER SAMSUNG ATOFINA CO. LTD. (KR) 2004-08-24 US claimed
CN-1454235-A Reactor alloy of syndiotactic polystyrene having high impact resistance SAMSUNG GENERAL CHEMICALS CO (KR) 2003-11-05 CN claimed
US-20030176581-A1 Reactor alloy of syndiotactic polystyrene having high impact resistance SAMSUNG ATOFINA GMBH & CO. LTD. (KR) 2003-09-18 US claimed
EP-1311612-A1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE Samsung General Chemicals Co., Ltd. (KR) 2003-05-21 EP claimed
WO-2002014425-A1 REACTOR ALLOY OF SYNDIOTACTIC POLYSTYRENE HAVING HIGH IMPACT RESISTANCE SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2002-02-21 WO claimed
EP-0505997-B1 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN CO (JP) 1997-05-28 EP claimed
US-5378777-A Styrene monomer substituted with silicon group, transition metal complex catalyst IDEMITSU KOSAN CO., LTD. (JP) 1995-01-03 US claimed
EP-0505997-A2 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545780-B2 Flexible metal clad laminates and methods of preparation thereof DSG1, CDH1, CAD ALDH1A1 480/4885TSHR 4638/4885PTGS2 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.