SCHEMBL585196

SCHEMBL585196

C=Cc1cccc(-c2cccc(C=C)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
PTGS2 P35354 1/20 0.53
ALDH1A1 P00352 3/20 0.52
TSHR P16473 1/20 0.52
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HDAC8 Q9BY41 3/20 0.38
TGFBR1 P36897 1/20 0.38
KCNH2 Q12809 1/20 0.37
BRD4 O60885 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30485440 1.00 TP53 (0.58) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL596121 0.97 TP53 (0.56) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL595061 0.95 PTGS2 (0.59) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL30618844 0.93 ALDH1A1 (0.59) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL714226 0.93 ALDH1A1 (0.59) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL2095987 0.91 PTGS2 (0.56) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL4257518 0.91 PTGS2 (0.56) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL8757855 0.91 ALDH1A1 (0.56) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL29870364 0.91 PTGS2 (0.56) TP53TDP1PTGS2ALDH1A1TSHR
Styrene SCHEMBL9129912 0.91 ALDH1A1 (0.64) TP53TDP1PTGS2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746116-B1 COPOLYMER, GRAFT COPOLYMER, GRAFT COPOLYMER PARTICLE, FLAME RETARDANT, AND RESIN COMPOSITION KANEKA CORP (JP) 2011-07-06 EP claimed
JP-8092322-A None JP disclosed
JP-2188536-A None JP disclosed
JP-2049088-A None JP disclosed
JP-2105824-A None JP disclosed
US-12545780-B2 Flexible metal clad laminates and methods of preparation thereof NOTARK CORPORATION (US) 2026-02-10 US disclosed
US-20260035495-A1 FUNCTIONAL COPOLYMERS AND METHODS OF PREPARATION THEREOF Kraton Corporation (US) 2026-02-05 US disclosed
US-20260014539-A1 HOLLOW PARTICLES AND PRODUCTION METHOD THEREFOR SANSUI CO., LTD. (JP) 2026-01-15 US disclosed
US-20250367910-A1 LAMINATES BASED ON COPOLYMERS OF DIISOALKENYLARENES NOTARK CORPORATION (US) 2025-12-04 US disclosed
US-12447719-B2 Metal-clad laminate, wiring board, resin-including metal foil, and resin composition PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-10-21 US disclosed
EP-0553801-B1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS (JP) 1997-04-23 EP disclosed
JP-H0892322-A CROSS-LINKED RESIN NIPPON STEEL CHEM CO LTD 1996-04-09 JP disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
US-5270439-A Method of producing a curable composition containing 4,4'-bis(methacryloylthio)diphenylsulfide SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-12-14 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5183917-A Curable; optics, coatings, seals, adhesives, paints SHOWA DENKO K.K. (JP) 1993-02-02 US disclosed
EP-0394495-A1 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1990-10-31 EP disclosed
JP-H02188536-A PRODUCTION OF 3,3'-DIVINYLBIPHENYL SHOWA DENKO KK 1990-07-24 JP disclosed
JP-H02105824-A CURABLE COMPOSITION SHOWA DENKO KK 1990-04-18 JP disclosed
JP-H0249088-A CURABLE COMPOSITION SHOWA DENKO KK 1990-02-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035495-A1 FUNCTIONAL COPOLYMERS AND METHODS OF PREPARATION THEREOF VCL, FGB, CDH1 TP53 3478/4885TDP1 1777/4885PTGS2 910/4885
US-20260014539-A1 HOLLOW PARTICLES AND PRODUCTION METHOD THEREFOR GJB2, GJA1, PARL TP53 197/4885TDP1 2209/4885PTGS2 2164/4885
US-12545780-B2 Flexible metal clad laminates and methods of preparation thereof DSG1, CDH1, CAD TP53 3077/4885TDP1 1794/4885PTGS2 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.