Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 10/20 | 0.40 |
| ▸ | CA9 | Q16790 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 7/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512410 | 0.85 | CA2 (0.41) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4496657 | 0.84 | CA2 (0.40) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4517316 | 0.81 | ESR1 (0.41) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4506268 | 0.81 | CA1 (0.44) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4507406 | 0.79 | CA2 (0.38) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4496636 | 0.77 | MEN1 (0.36) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4559508 | 0.76 | CA1 (0.60) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4516373 | 0.76 | CYP1A2 (0.41) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4509260 | 0.76 | HTT (0.43) | CA2CA1CA9LMNACA12 | |
| SCHEMBL4509210 | 0.76 | CA1 (0.43) | CA2CA1CA9LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234014-A1 | Naphthalene-Disulfonamides Useful for the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234014-A1 | Naphthalene-Disulfonamides Useful for the Treatment of Inflammation | AREG, PRSS12, CXCL8 | CA2 2959/4885CA1 3172/4885CA9 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.