Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.59 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849775 | 1.00 | PDK1 (0.59) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL28225535 | 0.87 | RORC (0.55) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL6403303 | 0.87 | HDAC3 (0.48) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL30278664 | 0.85 | MEN1 (0.48) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL16953907 | 0.85 | HDAC3 (0.47) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL835653 | 0.85 | MEN1 (0.48) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL1684396 | 0.85 | CYP17A1 (0.58) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL4598556 | 0.84 | MAPT (0.62) | PDK1PDK2PDK3PDK4SIRT2 | |
| SCHEMBL29029431 | 0.84 | HDAC3 (0.56) | MAPTLMNARORCHSD17B10MAPK1 | |
| SCHEMBL22669530 | 0.84 | HDAC3 (0.46) | PDK1PDK2PDK3PDK4SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864380-B1 | CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-02-01 | — | — | EP | claimed |
| US-20150183688-A1 | CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2015-07-02 | — | — | US | claimed |
| EP-2864380-A1 | CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS | Construction Research & Technology GmbH (DE) | 2015-04-29 | — | — | EP | claimed |
| WO-2014001064-A1 | CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2014-01-03 | — | — | WO | claimed |
| US-4657593-A | USING AN THERMOSTABLE, HYDROPHILIC ALDOL CONDENSATION POLYMER OF AN ALDEHYDE AND KETONE | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1987-04-14 | — | — | US | claimed |
| CN-116546990-B | CD73 inhibitor and pharmaceutical application thereof | RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| EP-3474901-B1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B V (NL) | 2025-08-06 | — | — | EP | disclosed |
| US-12186405-B2 | Cleavable tetrazine used in bio-orthogonal drug activation | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2025-01-07 | — | — | US | disclosed |
| CN-114539340-B | CD73 inhibitor and pharmaceutical application thereof | 润佳（苏州）医药科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116546990-A | CD73 inhibitor and pharmaceutical application thereof | 润佳（苏州）医药科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| US-5705599-A | ANTISWELLING AGENTS FOR CLAYS | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| US-5597915-A | ANTAGONISTS OF CHOLECYSTOKININ AND GASTRIN RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 1997-01-28 | — | — | US | disclosed |
| EP-0637308-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993019063-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
| US-5220018-A | Benzodiazepine derivatives | MERCK & CO., INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0508796-A1 | Cholecystokinin antagonists | MERCK & CO. INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-4657593-A | USING AN THERMOSTABLE, HYDROPHILIC ALDOL CONDENSATION POLYMER OF AN ALDEHYDE AND KETONE | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1987-04-14 | — | — | US | disclosed |
| US-4585853-A | Acid group-containing hydrophilic co-condensation products of ketone-aldehyde resins | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | KIT, TPSB2, BTD | PDK1 913/4885PDK2 886/4885PDK3 636/4885 |
| US-12186405-B2 | Cleavable tetrazine used in bio-orthogonal drug activation | KIT, TPSB2, BTD | PDK1 913/4885PDK2 886/4885PDK3 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.