Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | DUSP1 | P28562 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526536 | 0.90 | LMNA (0.79) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL4512212 | 0.87 | TP53 (0.65) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL4513229 | 0.86 | TP53 (0.65) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL4518500 | 0.86 | MAPT (0.75) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL4514921 | 0.85 | DUSP1 (0.72) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL3145506 | 0.85 | TP53 (0.61) | HPGDHSD17B10TP53MAPTLMNA | |
| SCHEMBL4503739 | 0.84 | TP53 (0.84) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL4526889 | 0.84 | TP53 (0.59) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL26687955 | 0.84 | TP53 (0.82) | HPGDHSD17B10GAATP53MAPT | |
| SCHEMBL2242896 | 0.84 | MAPT (0.73) | HPGDHSD17B10TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | HPGD 411/4885HSD17B10 2367/4885GAA 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.