Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500106 | 0.91 | HTT (0.34) | HTTCES1 | |
| SCHEMBL4512633 | 0.81 | GAA (0.46) | ALDH1A1HTTMAPTGAAHTR2C | |
| SCHEMBL4503903 | 0.80 | HTT (0.33) | HTT | |
| SCHEMBL4495559 | 0.78 | — | — | |
| SCHEMBL4499948 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MAPTHTR6GAA | |
| SCHEMBL11212064 | 0.70 | PKM (0.41) | ALDH1A1HTTMAPTL3MBTL1CES1 | |
| SCHEMBL11224153 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HTTMAPTL3MBTL1HTR6 | |
| SCHEMBL11232896 | 0.68 | PDE7A (0.38) | PDE7A | |
| SCHEMBL10911402 | 0.67 | MAPT (0.38) | ALDH1A1HTTMAPTGAA | |
| SCHEMBL6314284 | 0.66 | L3MBTL1 (0.34) | L3MBTL1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547660-B2 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | BAYER AKTIENGESELLSCHAFT (DE) | 2009-06-16 | — | — | US | disclosed |
| EP-1276741-B1 | PHENYL SUBSTITUTED 4-HYDROXY TETRAHYDROPYRIDONE AND ITS USE AS PESTICIDE AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-6974827-B2 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-12-13 | — | — | US | disclosed |
| US-20050256089-A1 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | FISCHER REINER | 2005-11-17 | — | — | US | disclosed |
| US-20030176464-A1 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176464-A1 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | CYP4X1, DDT, CYP1B1 | ALDH1A1 88/4885HTT 129/4885MAPT 2916/4885 |
| US-20050256089-A1 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | DDT, CYP4X1, CYP4B1 | ALDH1A1 297/4885HTT 48/4885MAPT 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.