Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499948 | 0.86 | ALDH1A1 (0.34) | GAATP53MAPTALDH1A1KMT2A | |
| SCHEMBL4501688 | 0.81 | ALDH1A1 (0.31) | GAAMAPTALDH1A1HTTHTR2C | |
| SCHEMBL10737556 | 0.80 | KMT2A (0.47) | GAAMAPK1TP53MAPTUSP2 | |
| SCHEMBL4500106 | 0.76 | HTT (0.34) | TP53HTT | |
| SCHEMBL11223029 | 0.74 | MAPK1 (0.42) | GAAMAPK1TP53MAPTUSP2 | |
| SCHEMBL7769009 | 0.73 | GAA (0.42) | GAAMAPK1TP53MAPTUSP2 | |
| SCHEMBL7780304 | 0.72 | TP53 (0.40) | GAAMAPK1TP53MAPTUSP2 | |
| SCHEMBL10896846 | 0.71 | GAA (0.46) | GAATP53MAPTALDH1A1HTT | |
| SCHEMBL11219061 | 0.71 | HTR1A (0.42) | GAATP53MAPTALDH1A1HTT | |
| SCHEMBL12496757 | 0.70 | PDE7A (0.45) | GAATP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547660-B2 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | BAYER AKTIENGESELLSCHAFT (DE) | 2009-06-16 | — | — | US | disclosed |
| EP-1276741-B1 | PHENYL SUBSTITUTED 4-HYDROXY TETRAHYDROPYRIDONE AND ITS USE AS PESTICIDE AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-6974827-B2 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-12-13 | — | — | US | disclosed |
| US-20050256089-A1 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | FISCHER REINER | 2005-11-17 | — | — | US | disclosed |
| US-20030176464-A1 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176464-A1 | Phenyl substituted 4-hydroxy tetrahydroxypyridone | CYP4X1, DDT, CYP1B1 | GAA 1244/4885MAPK1 2537/4885TP53 2896/4885 |
| US-20050256089-A1 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | DDT, CYP4X1, CYP4B1 | GAA 1030/4885MAPK1 4010/4885TP53 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.