Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 5/20 | 0.38 |
| ▸ | LDHB | P07195 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502224 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4518405 | 0.71 | POLB (0.36) | LDHALDHBALDH1A1MAPTPOLB | |
| SCHEMBL4510951 | 0.70 | FEN1 (0.51) | LDHALDHBEGLN1L3MBTL1ALB | |
| SCHEMBL4518939 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KDM4EEGLN1L3MBTL1MEN1 | |
| SCHEMBL474786 | 0.68 | KDM4E (0.37) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL1685948 | 0.67 | ALDH1A1 (0.77) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL4501941 | 0.67 | NOTUM (0.32) | ALDH1A1KDM4E | |
| SCHEMBL8129315 | 0.67 | KDM4E (0.47) | HSD17B10LDHALDHBALDH1A1KDM4E | |
| SCHEMBL11234096 | 0.67 | KMT2A (0.44) | HSD17B10LDHALDHBALDH1A1KDM4E | |
| SCHEMBL31384761 | 0.66 | LDHA (0.43) | HSD17B10LDHALDHBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553849-B2 | Compounds | ACTIVE BIOTECH AB (SE) | 2009-06-30 | — | — | US | disclosed |
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| US-20060004038-A1 | Novel compounds | ACTIVE BIOTECH AB (SE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004038-A1 | Novel compounds | REL, CLIC4, C5 | GFER 484/4885HSD17B10 2141/4885LDHA 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.