Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518405 | 0.82 | POLB (0.36) | ALDH1A1 | |
| SCHEMBL4510951 | 0.70 | FEN1 (0.51) | — | |
| SCHEMBL4509027 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4501800 | 0.67 | GFER (0.39) | KDM4EALDH1A1 | |
| SCHEMBL26784147 | 0.66 | ALDH1A1 (0.44) | NOTUMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29463790 | 0.65 | ALDH1A1 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL17713228 | 0.65 | ALDH1A1 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL4504058 | 0.64 | KMT2A (0.57) | KDM4EALDH1A1 | |
| SCHEMBL31384761 | 0.63 | LDHA (0.43) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL27815596 | 0.63 | MEN1 (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980937-B | Thienopyridone carboxamides and their medical use | ACTIVE BIOTECH AB | 2011-08-10 | — | — | CN | disclosed |
| US-7553849-B2 | Compounds | ACTIVE BIOTECH AB (SE) | 2009-06-30 | — | — | US | disclosed |
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| CN-1980937-A | Thienopyridone carboxamides and their medical use | ACTIVE BIOTECH AB (SE) | 2007-06-13 | — | — | CN | disclosed |
| US-20060004038-A1 | Novel compounds | ACTIVE BIOTECH AB (SE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004038-A1 | Novel compounds | REL, CLIC4, C5 | NOTUM 2268/4885KDM4E 1493/4885ALDH1A1 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.