SCHEMBL450310

SCHEMBL450310

O=C1C(c2ccccc2)=C(c2ccccc2)C(=O)N1OS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.69
MEN1 O00255 3/20 0.69
KDM4E B2RXH2 6/20 0.57
ALDH1A1 P00352 6/20 0.57
MAPT P10636 5/20 0.57
HPGD P15428 5/20 0.57
PARL Q9H300 2/20 0.56
VDR P11473 2/20 0.53
HTT P42858 1/20 0.49
PTGS2 P35354 7/20 0.48
PTGS1 P23219 5/20 0.48
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.43
PKM P14618 1/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2902348 0.90 KDM4E (0.69) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL450776 0.86 VDR (0.72) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL2903856 0.85 KDM4E (0.51) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL27489087 0.82 KDM4E (0.53) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL2468373 0.82 KMT2A (1.00) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL2902793 0.81 KMT2A (0.45) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL28954361 0.78 KMT2A (0.42) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL14509461 0.77 KMT2A (0.68) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL27975286 0.77 KMT2A (0.41) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL382979 0.76 PTGS2 (0.41) KMT2AMEN1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US claimed
CN-122043858-A EUV patterned resist formation method 亚历克斯·P·G·罗宾逊 2026-05-15 CN disclosed
CN-119937243-A Chemically amplified positive photosensitive resin composition, cured film, and element having cured film 奇美实业股份有限公司 2025-05-06 CN disclosed
US-20240199854-A1 COMPOSITION, CURED FILM, STRUCTURAL BODY, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD OF CURED FILM FUJIFLIM CORPORATION (JP) 2024-06-20 US disclosed
EP-3010943-B1 CURABLE COMPOSITION, FILM, AND METHOD OF PRODUCING FILM CANON KK (JP) 2024-04-03 EP disclosed
WO-2024057999-A1 COLORING COMPOSITION, CURED FILM, COLOR FILTER, DISPLAY DEVICE AND METHOD FOR PRODUCING CURED FILM 富士フイルム株式会社 2024-03-21 WO disclosed
CN-111324013-B Chemically amplified positive photosensitive resin composition and application thereof 奇美实业股份有限公司 2023-12-01 CN disclosed
WO-2023210418-A1 THERMOSETTING COMPOSITION, CURED PRODUCT, AND OPTICAL MEMBER 富士フイルム株式会社 2023-11-02 WO disclosed
CN-116360211-A Chemically amplified positive photosensitive resin composition, protective film, and element having protective film 奇美实业股份有限公司 2023-06-30 CN disclosed
CN-111381438-B Chemically amplified positive photosensitive resin composition and application thereof 奇美实业股份有限公司 2023-06-20 CN disclosed
US-6136500-A CONTAINS A PHOTOACID GENERATOR COMPRISING A COMBINATION OF A COMPOUND THAT GENERATES A CARBOXYLIC ACID UPON EXPOSURE TO RADIATION AND ANOTHER COMPOUND THAT GENERATES ANOTHER ACID UPON EXPOSURE TO RADIATION JSR CORPORATION (JP) 2000-10-24 US disclosed
US-6120972-A COPOLYMER OF ACRYLIC ESTER AND CARBONATE WITH PHOTOACID GENERATOR FOR PHOTOSENSITIVE ELEMENTS JSR CORPORATION (JP) 2000-09-19 US disclosed
EP-1031880-A1 POSITIVE RADIATION-SENSITIVE COMPOSITION TORAY INDUSTRIES, INC. (JP) 2000-08-30 EP disclosed
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US disclosed
EP-0959389-A1 Diazodisulfone compound and radiation-sensitive resin composition JSR Corporation (JP) 1999-11-24 EP disclosed
US-5962180-A COMPRISING (A) A COPOLYMER COMPRISING RECURRING UNITS OF A P-HYDROXYSTYRENE UNIT AND A STYRENE UNIT HAVING AN ACETAL GROUP OR A KETAL GROUP AT THE P-POSITION, (B) A COPOLYMER COMPRISING RECURRING UNITS OF A T-BUTYL (METH)ACRYLATE UNIT JSR CORPORATION (JP) 1999-10-05 US disclosed
EP-0901043-A1 Radiation-sensitive resin composition JSR Corporation (JP) 1999-03-10 EP disclosed
EP-0898201-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-02-24 EP disclosed
EP-0843220-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-20 EP disclosed
EP-0793144-A2 Radiation sensitive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-09-03 EP disclosed