Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.77 |
| ▸ | HTR1A | P08908 | 6/20 | 0.77 |
| ▸ | HTR1B | P28222 | 6/20 | 0.77 |
| ▸ | HTR2A | P28223 | 9/20 | 0.67 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512060 | 0.87 | HTR1A (1.00) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7809324 | 0.86 | HTR1A (0.97) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL9006903 | 0.84 | HTR1D (0.54) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL8445909 | 0.81 | HTR1A (0.52) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL11924512 | 0.80 | HTR1A (0.51) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL1971468 | 0.80 | HTR2A (1.00) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL25260689 | 0.80 | HTR2A (0.57) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL29804890 | 0.80 | HTR2A (0.57) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6087688 | 0.79 | HTR2A (0.97) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL2537626 | 0.77 | HTR2A (0.74) | HTR1DHTR1AHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047580-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | MAGICMED INDUSTRIES INC. (CA) | 2022-03-10 | — | — | WO | disclosed |
| US-7612099-B2 | Vinylogous acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-11-03 | — | — | US | disclosed |
| CN-101321749-A | Novel vinylogous acid derivatives | HOFFMANN LA ROCHE (CH) | 2008-12-10 | — | — | CN | disclosed |
| EP-1957483-A1 | NOVEL VINYLOGOUS ACIDS DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063010-A1 | NOVEL VINYLOGOUS ACIDS DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-07 | — | — | WO | disclosed |
| US-20070129421-A1 | Vinylogous acid derivatives | HOFFMANN-LA ROCHE INC. | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129421-A1 | Vinylogous acid derivatives | CMA1, TPSG1, TPSAB1 | HTR1D 1799/4885HTR1A 1692/4885HTR1B 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.