Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HLCS | P50747 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18527023 | 1.00 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL9800093 | 0.98 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL10380869 | 0.97 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL3499721 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL1423906 | 0.93 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL7717336 | 0.92 | CYP1A2 (0.42) | ALDH1A1L3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL5872353 | 0.88 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL22190342 | 0.88 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL22201153 | 0.88 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL9646435 | 0.88 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175491-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TORRENT PHARMACEUTICALS LIMITED (IN) | 2019-06-13 | — | — | US | claimed |
| EP-3471698-A1 | TOPICAL COMPOSITIONS OF APREMILAST | Torrent Pharmaceuticals Limited (IN) | 2019-04-24 | — | — | EP | claimed |
| WO-2017216738-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TORRENT PHARMACEUTICALS LIMITED (IN) | 2017-12-21 | — | — | WO | claimed |
| CN-120157874-A | High-elasticity light nylon elastomer and hydrolytic polymerization preparation method thereof | 浙江恒逸石化研究院有限公司 | 2025-06-17 | — | — | CN | disclosed |
| US-12007001-B2 | Cellulose-containing gear | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-06-11 | — | — | US | disclosed |
| EP-4040018-B1 | A MOLDED ARTICLE | ASAHI CHEMICAL IND (JP) | 2024-05-22 | — | — | EP | disclosed |
| EP-4353782-A1 | RESIN COMPOSITION AND METHOD FOR PRODUCING SAME | Asahi Kasei Kabushiki Kaisha (JP) | 2024-04-17 | — | — | EP | disclosed |
| WO-2023243587-A1 | FILLER-CONTAINING POLYPROPYLENE RESIN COMPOSITION | 三井化学株式会社 | 2023-12-21 | — | — | WO | disclosed |
| CN-112955496-B | Fiber-reinforced resin material and method for producing same | 东丽株式会社 | 2023-10-20 | — | — | CN | disclosed |
| WO-2023190722-A1 | CURABLE ADHESIVE COMPOSITION FOR BATTERY, BATTERY MODULE, AND BATTERY PACK | 積水ポリマテック株式会社 | 2023-10-05 | — | — | WO | disclosed |
| US-11680165-B2 | Polyamide resin composition with high fluidity | MITSUI CHEMICALS, INC. (JP) | 2023-06-20 | — | — | US | disclosed |
| US-5648423-A | MOLDINGS OF POLYAMIDE BLENDS WITH BUTYLENE-ETHYLENE COPOLYMER WITH UNSATURATED CARBOXYLIC ACID | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0754731-A2 | Polyamide resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0739948-A1 | FOAMABLE RESIN COMPOSITION, FOAM PRODUCED THEREFROM, AND PROCESS FOR PRODUCING THE FOAM | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1996-10-30 | — | — | EP | disclosed |
| EP-0668323-A1 | POLYAMIDE RESIN COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5221707-A | Of coating resin and a blocked polyurethane prepolymer adhesion promoter | GENCORP INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0517471-A2 | Coating blend compositions | GENCORP INC. (US) | 1992-12-09 | — | — | EP | disclosed |
| US-5115007-A | Curable composition of hydroxy polydiene with polyisocyanate coated on a substrate | GENCORP INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0461835-A2 | Method for purifying organic solution containing lactams | UBE INDUSTRIES, LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4610768-A | MIXING WITH HYDROCARBONS, DISTILLATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175491-A1 | TOPICAL COMPOSITIONS OF APREMILAST | TSLP, APRT, TPSB2 | ALDH1A1 61/4885L3MBTL1 4864/4885S1PR2 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.