Isopentyl 2-Cyanoacrylate

Isopentyl 2-Cyanoacrylate

SCHEMBL450802

C=C(C#N)C(=O)OCCC(C)C

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP19A1 P11511 1/20 0.41
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
PKM P14618 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 1/20 0.33
ACHE P22303 1/20 0.33
PPARG P37231 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316485 0.89 TSHR (0.55) TSHRALDH1A1CYP19A1TDP1ACHE
SCHEMBL1924506 0.88 TSHR (0.53) TSHRALDH1A1CYP19A1TDP1ACHE
SCHEMBL28744654 0.87 TSHR (0.56) TSHRALDH1A1CYP19A1THRBCHRNB2
SCHEMBL20943619 0.87 TSHR (0.49) TSHRALDH1A1CYP19A1KMT2ALMNA
SCHEMBL15520522 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1
SCHEMBL15519654 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1
SCHEMBL5580248 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1
SCHEMBL21932806 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1
SCHEMBL4578805 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1
SCHEMBL4621788 0.86 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO claimed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP claimed
CN-111278938-B Toughened low odor/low bloom cyanoacrylate compositions 汉高股份有限及两合公司 2023-06-20 CN claimed
CN-115627124-A Low-whitening impact-resistant quick-drying adhesive composition and preparation method thereof 上海兰盛新材料科技有限公司 2023-01-20 CN claimed
CN-111278878-B Cyanoacrylate compositions 汉高股份有限及两合公司 2022-08-26 CN claimed
US-20220025552-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) 2022-01-27 US claimed
EP-3700950-A1 CYANOACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-09-02 EP claimed
EP-3700991-A1 TOUGHENED, LOW ODOR/LOW BLOOM CYANOACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-09-02 EP claimed
US-20200255692-A1 CYANOACRYLATE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2020-08-13 US claimed
US-20200255693-A1 TOUGHENED, LOW ODOR/LOW BLOOM CYANOACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-08-13 US claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 EP claimed
US-5665107-A Surface opening adhesive sealer HEMODYNAMICS, INC. (US) 1997-09-09 US claimed
US-5653730-A Surface opening adhesive sealer HEMODYNAMICS, INC. (US) 1997-08-05 US claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 WO claimed
US-5529577-A Surface opening adhesive sealer HEMODYNAMICS, INC. (US) 1996-06-25 US claimed
US-5383899-A Method of using a surface opening adhesive sealer HEMODYNAMICS, INC. 1995-01-24 US claimed
US-3940362-A Cross-linked cyanoacrylate adhesive compositions JOHNSON & JOHNSON (US) 1976-02-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF TSHR 148/4885ALDH1A1 3677/4885CYP19A1 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.